Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma
Summary
The lay summary the sponsor registered on ClinicalTrials.gov.
Investigators
The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.
- Sabine Mueller, MD, PhD
University of California, San Francisco
Principal Investigator - Santhosh A Upadhyaya, MD
University of Michigan, C. S. Mott Children's Hospital
Study Chair
A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.
Sites
10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.
- University of Alabama at Birmingham, Children'S of Alabama
Birmingham, Alabama, United States
Recruiting - Ucsf Benioff Children'S Hospital, University of California, San Francisco
San Francisco, California, United States
Sabine Mueller, MD, PhDRecruiting - Children'S National Hospital
Washington D.C., District of Columbia, United States
Not, yet, recruiting - Johns Hopkins Hospital
Baltimore, Maryland, United States
Recruiting - University of Michigan, C.S. Mott Children'S Hospital
Ann Arbor, Michigan, United States
Not, yet, recruiting - St. Louis Children'S Hospital, Washington University in St. Louis
St Louis, Missouri, United States
Recruiting - Joseph M. Sanzari Children'S Hospital at Hackensack University Medical Center
Hackensack, New Jersey, United States
Not, yet, recruiting - Duke University Medical Center
Durham, North Carolina, United States
Recruiting - St. Jude Children'S Research Hospital
Memphis, Tennessee, United States
Not, yet, recruiting - University of Utah, Primary Children'S Hospital
Salt Lake City, Utah, United States
Not, yet, recruiting
Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.
Drugs studied
The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.
Registration & key dates
Registry attributes as recorded on the ClinicalTrials.gov study record.
- Start
- 5 May 2026
- Primary completion
- 30 Apr 2028
- Completion
- 31 Mar 2030
- Last update posted
- 19 Aug 2026
- Registered enrollment
- 30
- Registry id
- NCT07226453
Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.