Clinical trialNCT07240831RecruitingInterventional

Accuracy of a Cuffless Photoplethysmography (PPG) Chest-Patch Monitor for 24-hour Ambulatory Blood Pressure Monitoring (ABPM)

SponsorBiobeat Technologies Ltd.Enrollment600Blood PressureBlood Pressure MonitoringHeart DiseaseHypertension (HTN)

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study aims to validate the accuracy and reliability of blood pressure (BP) estimates obtained over 24 hours using a PPG-based chest-patch device compared to the gold standard ambulatory blood pressure monitoring (ABPM) method using an upper arm cuff-based oscillometric BP device, in both hypertensive and normotensive individuals referred by their provider to undergo a 24-hours ABPM for clinical indication. The Awake/Asleep test, which is the primary test recommended for automated wearable cuffless BP devices that are cuff-calibrated (based on the 2023 European Society of Hypertension (ESH) recommendations for the validation of cuffless blood pressure measuring devices), will be conducted in this study. The secondary aim of the study is to assess the feasibility and convenience of the PPG-based device.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Ziad Zoghby, M.D., M.B.A.
Mayo Clinic College of Medicine
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

11 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Israel

Haemek Hospital
Afula, Israel
Completed
the Holy Family Hospital Nazareth
Nazareth, Israel
Completed
Sheba Medical Center
Ramat Gan, Israel
Completed
Maccabi Healthcare
Tel Aviv, Israel
Completed

Italy

Instituto Auxologico Italiano
Milan, Italy
Prof. Gianfranco Parati Parati, MD
Recruiting

United States

Cardiology, P.C.
Birmingham, Alabama, United States
Ferrell O. Mendelsohn, MD
Recruiting
Mayo Clinic
Scottsdale, Arizona, United States
Sayeed Khalillullah, MD
Recruiting
Mayo Clinic
Jacksonville, Florida, United States
Lyle W. Baker, MD
Recruiting
U Health-University of Miami Health System
Miami, Florida, United States
Maria Delgado, MD
Recruiting
Henry Ford Health System
Detroit, Michigan, United States
Amir Kaki, MD
Recruiting
Mayo Clinic
Rochester, Minnesota, United States
Ziad Zoghby, MD, MBA
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 15 Dec 2025
Primary completion: 30 Oct 2026
Completion: 30 Oct 2026
Last update posted: 13 Aug 2026
Registered enrollment: 600
Registry id: NCT07240831

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.