Clinical trialNCT07271355Not, yet, recruitingPhase 3Interventional

Pressurized Intraperitoneal Aerosolized Chemotherapy With Mitomycin for the Treatment of Unresectable Appendix or Colorectal Cancer With Peritoneal Metastases, The IMPACT Trial

SponsorCity of Hope Medical CenterEnrollment129Metastatic Appendix CarcinomaMetastatic Colorectal CarcinomaMetastatic Malignant Neoplasm in the PeritoneumStage IV Appendix Carcinoma AJCC v8Stage IVC Colorectal Cancer AJCC v8Unresectable Colorectal Carcinoma

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Mustafa Raoof
City of Hope Medical Center
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Ctca at Western Regional Medical Center
Goodyear, Arizona, United States
Mustafa Raoof
City of Hope Comprehensive Cancer Center
Duarte, California, United States
Mustafa Raoof
City of Hope at Irvine Lennar
Irvine, California, United States
Mustafa Raoof
City of Hope Atlanta Cancer Center
Newnan, Georgia, United States
Mustafa Raoof
City of Hope at Chicago
Zion, Illinois, United States
Mustafa Raoof

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Jul 2026
Primary completion: 28 Feb 2031
Completion: 28 Feb 2031
Last update posted: 9 Dec 2025
Registered enrollment: 129
Registry id: NCT07271355

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.