Clinical trialNCT07279467RecruitingObservational

Study of Oral Food Challenge Biomarkers (SAFER)

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment500Allergy

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a multi-center, mechanistic study. It is designed to learn more about signs in the body, called biomarkers, that might show if someone will have a reaction to peanut during a feeding test. The trial will enroll children ages 12 months to17 years old who are suspected of having an allergy to peanut. The primary objective is to identify a biomarker (or a combination of biomarkers) that will predict oral food challenge (OFC) (feeding test) results for participants with suspected peanut allergy.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Charles Schuler, M.D.
The University of Michigan: Division of Allergy and Clinical Immunology
Study Chair
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Robert Wood, M.D.
Johns Hopkins Children's Center: Department of Allergy & Immunology
Study Chair
clinicaltrials.gov ↗
Supinda Bunyavanich, M.D., M.P.H., M.Phil.
Icahn School of Medicine at Mount Sinai: Department of Pediatrics Allergy & Immunology
Study Chair
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Arkansas Children'S Hospital Research Institute: Department of Pediatrics, Allergy & Immunology
Little Rock, Arkansas, United States
Stacie Jones, MD
Recruiting
Stanford School of Medicine: Sean N. Parker Center for Allergy & Asthma Research
Palo Alto, California, United States
Sayantani Sindher, MD
Recruiting
Lurie Children'S Hospital of Chicago
Chicago, Illinois, United States
Ruchi Gupta, MD
Recruiting
Johns Hopkins Children'S Center: Department of Allergy & Immunology
Baltimore, Maryland, United States
Robert Wood, MD
Recruiting
Boston Children'S Hospital: Allergy and Asthma Program
Boston, Massachusetts, United States
Rima Rachid, MD
Not, yet, recruiting
the University of Michigan: Division of Allergy and Clinical Immunology
Ann Arbor, Michigan, United States
James Baker, MD
Recruiting
Icahn School of Medicine at Mount Sinai: Department of Pediatrics Allergy & Immunology
New York, New York, United States
Scott Sicherer, MD
Recruiting
North Carolina Children'S Hospital: Department of Pediatrics, Division of Allergy, Immunology and Rheumatology
Chapel Hill, North Carolina, United States
Edwin Kim, MD, MS
Recruiting
Cincinnati Children'S Hospital Medical Center: Division of Allergy and Immunology
Cincinnati, Ohio, United States
Amal Assa'ad, MD
Not, yet, recruiting
Vanderbilt University Medical Center: Division of Pediatric Allergy, Immunology, and Pulmonary Medicine
Nashville, Tennessee, United States
Leonard Bacharier, MD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Oral Food Challenge: Peanut Protein

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 20 Aug 2026
Primary completion: 1 Dec 2027
Completion: 1 Dec 2027
Last update posted: 23 Oct 2026
Registered enrollment: 500
Registry id: NCT07279467

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.