Clinical trialNCT07279467Not, yet, recruitingObservational

Study of Oral Food Challenge Biomarkers (SAFER)

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment500Allergy

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a multi-center, mechanistic study. It is designed to learn more about signs in the body, called biomarkers, that might show if someone will have a reaction to peanut during a feeding test. The trial will enroll children ages 12 months to17 years old who are suspected of having an allergy to peanut. The primary objective is to identify a biomarker (or a combination of biomarkers) that will predict oral food challenge (OFC) (feeding test) results for participants with suspected peanut allergy.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Charles Schuler, M.D.
The University of Michigan: Division of Allergy and Clinical Immunology
Study Chair
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Robert Wood, M.D.
Johns Hopkins Children's Center: Department of Allergy & Immunology
Study Chair
clinicaltrials.gov ↗
Supinda Bunyavanich, M.D., M.P.H., M.Phil.
Icahn School of Medicine at Mount Sinai: Department of Pediatrics Allergy & Immunology
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Arkansas Children'S Hospital Research Institute: Department of Pediatrics, Allergy & Immunology
Little Rock, Arkansas, United States
Stanford School of Medicine: Sean N. Parker Center for Allergy & Asthma Research
Palo Alto, California, United States
Northwestern University Feinberg School of Medicine: Allergy Division
Chicago, Illinois, United States
Johns Hopkins Children'S Center: Department of Allergy & Immunology
Baltimore, Maryland, United States
Boston Children'S Hospital: Allergy and Asthma Program
Boston, Massachusetts, United States
the University of Michigan: Division of Allergy and Clinical Immunology
Detroit, Michigan, United States
Icahn School of Medicine at Mount Sinai: Department of Pediatrics Allergy & Immunology
New York, New York, United States
North Carolina Children'S Hospital: Department of Pediatrics, Division of Allergy, Immunology and Rheumatology
Chapel Hill, North Carolina, United States
Cincinnati Children'S Hospital Medical Center: Division of Allergy and Immunology
Cincinnati, Ohio, United States
Vanderbilt University Medical Center: Division of Pediatric Allergy, Immunology, and Pulmonary Medicine
Nashville, Tennessee, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Oral Food Challenge: Peanut Protein

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Apr 2026
Primary completion: 1 Oct 2027
Completion: 1 Oct 2027
Last update posted: 12 Dec 2025
Registered enrollment: 500
Registry id: NCT07279467

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.