Clinical trialNCT07293689RecruitingObservational

PREcision MEDicine In Achalasia (PREMEDIA) - Cohort

SponsorNorthwestern UniversityEnrollment200Distal Esophageal SpasmEGJ Outflow Obstruction With Spastic/Hypercontractile FeaturesJackhammer EsophagusType III Achalasia

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The goal of this observational study is to learn about how the doctor decides how long to cut t the esophageal muscle during Per-Oral Endoscopic Myotomy (POEM) in patients with difficulty swallowing due to certain conditions. The main question it aims to answer is: does pre-POEM testing help the physician choose how long to cut the muscle. Participants will allow researchers to access their standard of care information in their medical record, complete questionnaires at up to 6 times over a 2-year period.

clinicaltrials.gov ↗

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

15 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Mayo Clinic Arizona
Scottsdale, Arizona, United States
Not, yet, recruiting
University of California San Diego
La Jolla, California, United States
Not, yet, recruiting
University of Colorado Denver
Denver, Colorado, United States
Not, yet, recruiting
University of Florida
Gainesville, Florida, United States
Not, yet, recruiting
Adventist Health System/sunbelt, Inc
Orlando, Florida, United States
Not, yet, recruiting
Emory University
Atlanta, Georgia, United States
Anand Jain, MD
Recruiting
Northwestern University
Chicago, Illinois, United States
John Pandolfino, MD
Recruiting
Johns Hopkins University
Baltimore, Maryland, United States
Not, yet, recruiting
Washington University
St Louis, Missouri, United States
Not, yet, recruiting
Weill Cornell Medical College
New York, New York, United States
Not, yet, recruiting
Atrium Health/wake Forest
Charlotte, North Carolina, United States
Badih Elmunzer, MD
Recruiting
Case Western Reserve University
Cleveland, Ohio, United States
Not, yet, recruiting
Metrohealth Medical Center
Cleveland, Ohio, United States
Ronnie Fass, MD
Recruiting
Vanderbilt University Medical Center
Nashville, Tennessee, United States
Dhyanesh Patel, MD
Recruiting
Baylor Scott & White Health
Dallas, Texas, United States
Not, yet, recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Dec 2026
Primary completion: 31 Aug 2031
Completion: 31 Aug 2032
Last update posted: 17 Aug 2026
Registered enrollment: 200
Registry id: NCT07293689

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.