Clinical trialNCT07321106RecruitingPhase 1Interventional

A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Anti-tumor Activity of CBI-1214 T Cell Engager in Participants With Advanced or Metastatic MSS/MSI-L Colorectal Cancer

SponsorCartography BiosciencesEnrollment80Advanced Colorectal CancerCRCColon CancerColorectal (Colon or Rectal) CancerColorectal CancerColorectal Cancer (CRC)+1 more conditions

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

City of Hope Duarte
Duarte, California, United States
Marwan Fakih, MD
Recruiting
Ucla
Los Angeles, California, United States
J. Randolph Hecht, MD
Recruiting
Valkyrie Clinical Trials
Los Angeles, California, United States
David Berz, MD, PhD, MPH
Recruiting
Ucsf
San Francisco, California, United States
David Oh, MD, PhD
Recruiting
Emory Winship Cancer Institute
Atlanta, Georgia, United States
Olatunji Alese, MD
Recruiting
Start Midwest
Grand Rapids, Michigan, United States
Manish Sharma, MD
Recruiting
Next Oncology
San Antonio, Texas, United States
David Sommerhalder, MD
Recruiting
Next Oncology
Fairfax, Virginia, United States
Alexander Spira, MD, PhD
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

CBI-1214

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 15 Jan 2026
Primary completion: 30 Apr 2029
Completion: 31 Oct 2029
Last update posted: 10 Jun 2026
Registered enrollment: 80
Registry id: NCT07321106

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.