Clinical trialNCT07335510RecruitingInterventional

Impact of Barostimulation on Hemodynamics in Adults With Heart Failure

SponsorColumbia UniversityEnrollment58HFrEF - Heart Failure With Reduced Ejection Fraction

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study evaluates the effects of the implantation and adjustment of the CVRx Barostim device in adult patients with heart failure with reduced ejection fraction who are receiving maximally tolerated doses of guideline directed medical and device therapies. The study aims to assess how therapy using this device affects heart function, symptoms, and exercise capacity, with particular focus on how the device affects blood flow and heart pressures during exercise. Information from this study may help inform patient selection and device management in patients with heart failure.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Nir Uriel, MD
Columbia University
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

7 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of California San Francisco Health
San Francisco, California, United States
Liviu Klein, MD
Not, yet, recruiting
Medstar Health
Washington D.C., District of Columbia, United States
Farooq H. Sheikh, MDRicha Gupta, MD
Not, yet, recruiting
University of Chicago Medical Center
Chicago, Illinois, United States
Manreet Kanwar, MDMark Belkin, MD
Not, yet, recruiting
Columbia University Irving Medical Center
New York, New York, United States
Nir Uriel, MD
Recruiting
Montefiore Medical Center
New York, New York, United States
Ulrich P. Jorde, MD
Not, yet, recruiting
Weill Cornell Medicine
New York, New York, United States
Maria Karas, MD
Not, yet, recruiting
Medical University of South Carolina Health
Charleston, South Carolina, United States
Ryan J. Tedford, MD
Not, yet, recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Mar 2026
Primary completion: 31 Dec 2027
Completion: 31 Mar 2028
Last update posted: 29 Jun 2026
Registered enrollment: 58
Registry id: NCT07335510

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.