Clinical trialNCT07405645RecruitingInterventional

Stereotactic MRI-guided Focused Ultrasound Mesencephalotomy

SponsorUniversity of VirginiaEnrollment20Cancer PainHead Neck CancerSquamous Cell Cancer of Head and Neck (SCCHN)

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This phase 1 multi-site study investigates the safety and initial effectiveness of focused ultrasound lesioning of the contralateral mesencephalon for severe, opioid-resistant pain associated with head and neck cancer and brachial cancer.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

William J Elias, MD
University of Virginia
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

6 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Brigham and Women'S Hospital
Boston, Massachusetts, United States
Rees Cosgrove, MD
Not, yet, recruiting
Weill Cornell Medicine
New York, New York, United States
Michael Kaplitt, MD
Not, yet, recruiting
Oregon Health and Science University
Portland, Oregon, United States
Ahmed Raslan, MD
Not, yet, recruiting
the University of Texas Southwestern Medical Center
Dallas, Texas, United States
Nader Pouratian, MD
Not, yet, recruiting
Baylor College of Medicine
Houston, Texas, United States
Ashwin Viswanathan, MD
Not, yet, recruiting
University of Virginia
Charlottesville, Virginia, United States
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 15 Feb 2026
Primary completion: 31 Dec 2028
Completion: 31 Dec 2029
Last update posted: 12 Feb 2026
Registered enrollment: 20
Registry id: NCT07405645

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.