Clinical trialNCT07409103RecruitingPhase 2Interventional

A Study to Assess the Safety and Efficacy of Different Doses of ELV001 to Treat Active Rheumatoid Arthritis in Patients With an Inadequate Response to Methotrexate and Tumor Necrosis Factor Inhibition (START SYNERGY)

SponsorElevara Medicines LimitedEnrollment180Active Rheumatoid Arthritis

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

29 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

South Africa

Panorama Medical Center
Panorama, Cape Town, South Africa
Dr Ingrid Clara Louw
Recruiting
the Arthritis Clinical Trial Centre
Pinelands, Capetown, South Africa
Dr. Cathy Spargo
Recruiting
Winelands Medical Research Centre - Somerset West (dr Francois Bouwer Inc)
Somerset West, Capetown, South Africa
Dr Francois Bouwer
Recruiting
Crismo Research Centre - Bertha Gxowa Hospital
Germiston, Gauteng, South Africa
Dr Mpoti Belina Seboka
Recruiting
Netcare Jakaranda Hospital Suite 102
Pretoria, Gauteng, South Africa
Dr. Elsa Margaretha van Duuren
Recruiting
Netcare Umhlanga Medical Centre
Durban, KwaZulu-Natal, South Africa
Dr. Asokan Niaidoo
Recruiting
Winelands Medical Research Centre
Stellenbosch, Western Cape, South Africa
Dr. Helmuth Reuter
Recruiting

United States

Arizona Arthritis & Rheumatology Associates
Gilbert, Arizona, United States
Dr. Daniel Kreutz
Recruiting
Arizona Arthritis & Rheumatology Associates
Glendale, Arizona, United States
Dr. Nehad Solomon
Recruiting
Arizona Arthritis & Rheumatology Associates
Tucson, Arizona, United States
Dr. Romy Cabacungan
Recruiting
Solace Clinical Research - Populace Health (network)
Tustin, California, United States
Dr. Christine Kornu, MD
Recruiting
Denver Arthritis Clinic
Denver, Colorado, United States
Dr. Christopher R Antolini, MD
Recruiting
Rheumatology Associates of South Florida-Clinical Research Inc - Cliniverse Research (network)
Boca Raton, Florida, United States
Dr. Shawn Baca
Recruiting
Prophase, Llc - Clinitiative Health Research (network)
Margate, Florida, United States
Dr. Renan Amador
Recruiting
Millennium Medical Research Llc - Clinitiative Health Research (network)
Miami, Florida, United States
Dr. Ramon Moreda
Recruiting
Floridian Clinical Research, Llc - Clinitiative Health Research (network)
Miami Beach, Florida, United States
Dr. Christopher Mesa
Recruiting
Bioresearch Partner - Cliniverse Research (network)
South Miami, Florida, United States
Dr. Olga Kromo, MD
Recruiting
Accurate Clinical Research Inc (smo/ Network)
Lake Charles, Louisiana, United States
Dr. Enrique A Mendez, MD
Recruiting
Great Lakes Center of Rheumatology
Lansing, Michigan, United States
Dr. Joshua June, DO
Recruiting
Djl Clinical Research Pllc (network) Cirb
Charlotte, North Carolina, United States
Dr. Emily Jane Box
Recruiting
Carolina Arthritis Associates - Cliniverse Research (network)
Wilmington, North Carolina, United States
Dr. Mark D Harris
Recruiting
Altoona Arthritis & Osteoporosis Center
Duncansville, Pennsylvania, United States
Dr. Alan J Kivitz, MD, CPI
Recruiting
Pennsylvania Regional Center for Arthritis & Osteoporosis Research
Wyomissing, Pennsylvania, United States
Dr. Greg Emkey, MD
Recruiting
Accurate Clinical Management, Llc. - Accurate Clinical Research Inc (smo/ Network)
Baytown, Texas, United States
Dr. Sabeen Najam, MD
Recruiting
Accurate Clinical Research Inc (smo/ Network)
Houston, Texas, United States
Dr. Philip Waller, MD
Recruiting
Heights Rheumatology and Aesthetics - Es Clinical Research Group Network
Jackson, Texas, United States
Dr. Enelda M Agosto-Colon
Recruiting
Epic Medical Research-Red Oak
Red Oak, Texas, United States
Dr. Sunny Patel, MD
Recruiting
Dm Clinical Research (network)
Tomball, Texas, United States
Dr. Shaikh Arif Ali, MD
Recruiting
Dm Clinical Research (network)
Tomball, Texas, United States
Dr. Qaiser Rehman
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 18 Feb 2026
Primary completion: 15 Apr 2027
Completion: 31 Mar 2028
Last update posted: 23 Apr 2026
Registered enrollment: 180
Registry id: NCT07409103

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.