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Clinical trialNCT07419464RecruitingPhase 2Interventional

5-Fluorouracil Response and Optimization STudy (The FROST Trial)

SponsorWashington University School of MedicineEnrollment46Metastatic Squamous Cell CarcinomaRecurrent Squamous Cell Carcinoma of the Head and NeckSquamous Cell Carcinoma of Head and Neck
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Washington University School of Medicine

    St Louis, Missouri, United States

    Brendan Knapp, MDChristine Auberle, MDDouglas Adkins, MDEsther Lu, PhDJesse Zaretsky, MD, PhDPeter Oppelt, MD
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
21 Apr 2026
Primary completion
31 Jul 2028
Completion
31 Jul 2031
Last update posted
27 Apr 2026
Registered enrollment
46
Registry id
NCT07419464
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.