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Clinical trialNCT07423078RecruitingPhase 2Interventional

Window of Opportunity in Preserving Laryngeal Function Trial

SponsorMatthew SpectorEnrollment87Head and Neck Squamous Cell Carcinoma (HNSCC) - Recurrent/Metastatic (R/M)Hypopharyngeal Squamous Cell CarcinomaLocally Advanced Laryngeal Squamous Cell Carcinoma
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This trial will study the safety and tolerability and disease survival rates in adult patients with recurrent/metastatic (R/M) HNSCC when treated with carboplatin or cisplatin, paclitaxel, and toripalimab.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Upmc Hillman Cancer

    Pittsburgh, Pennsylvania, United States

    Matthew Spector, MD, FACS
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Carboplatin →Cisplatin →Paclitaxel →Toripalimab →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
6 Apr 2026
Primary completion
30 Apr 2029
Completion
30 Apr 2031
Last update posted
13 Apr 2026
Registered enrollment
87
Registry id
NCT07423078
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.