Clinical trialNCT07444814RecruitingPhase 1Interventional

Study Evaluating the Safety and Efficacy of HWK-007, a PTK7-directed Antibody Drug Conjugate in Participants With Advanced Solid Tumors

SponsorWhitehawk Therapeutics, Inc.Enrollment226Endometrial CancerNon-squamous EGFR Wt NSCLCOvarian CancerOvarian Cancer MetastaticOvarian Cancer Metastatic RecurrentPROC+1 more conditions

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Edward C Spindler, BS, MBA
Whitehawk Therapeutics
Study Director
clinicaltrials.gov ↗
Margaret C Dugan, MD
Whitehawk Therapeutics
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

12 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Arkansas
Little Rock, Arkansas, United States
Michael Birrer, MD
Not, yet, recruiting
Ucla - Hematology/oncology Clinical Research Unit
Los Angeles, California, United States
Aaron Lisberg, MD
Not, yet, recruiting
St. Francis Medical Center (osf Healthcare)
Peoria, Illinois, United States
Michelle Rowland, MD
Not, yet, recruiting
Start - Midwest
Grand Rapids, Michigan, United States
Manish Sharma
Recruiting
Hackensack University Medical Center - John Theurer Cancer Center
Hackensack, New Jersey, United States
Miguel Gonzalez, MD
Not, yet, recruiting
Roswell Park Comprehensive Care Center
Buffalo, New York, United States
Bailey Fitzgerald, MD
Not, yet, recruiting
University Hospital - Cleveland Medical Center
Cleveland, Ohio, United States
Matthew MIrsky, MD
Not, yet, recruiting
Next Oncology - Austin
Austin, Texas, United States
Recruiting
Next - Oncology - Houston
Houston, Texas, United States
Jennifer Segar, MD
Recruiting
Start - San Antonio
San Antonio, Texas, United States
Recruiting
Next Oncology - Virginia Cancer Specialists
Fairfax, Virginia, United States
Alexander Spira, MD, PhD
Recruiting
Fred Hutchinson Cancer Center
Seattle, Washington, United States
Lei Deng, MD
Not, yet, recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

HWK-007

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 19 Dec 2025
Primary completion: 31 Oct 2028
Completion: 31 Dec 2028
Last update posted: 27 Mar 2026
Registered enrollment: 226
Registry id: NCT07444814

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.