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Clinical trialNCT07476001RecruitingPhase 2Interventional

Phase 2a Study of High-Dose Testosterone Followed by Radioligand Therapy in mCRPC

SponsorH. Lee Moffitt Cancer Center and Research InstituteEnrollment12Metastatic Castration-resistant Prostate Cancer
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to evaluate whether high-dose testosterone followed by targeted radioligand therapy (TRT) is effective in treating metastatic castration resistant prostate cancer. Participants will be asked to spend about 6 months in this study. Participants will take study drug for 3.5 months.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Moffitt Cancer Center

    Tampa, Florida, United States

    Aakash Patel, MDAditi Patel, PA-CAlyssa Thompson, APRNAngel Johnson, APRNGhazal (Gigi) Jameel, APRNJingsong Zhang, MD, PhD →Jon Chatzkel, MDJuskaran Chadha, DOSarah Mizelle, PA-CTianshi (Mike) Liu, MD
    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

ADT with Luteinizing hormone-releasing hormone analogPSMA-617Testosterone →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
3 Mar 2026
Primary completion
30 Sept 2027
Completion
30 Sept 2027
Last update posted
15 May 2026
Registered enrollment
12
Registry id
NCT07476001
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.