Clinical trialNCT07521007RecruitingPhase 2Interventional

A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis

SponsorBeijing Inno Medicine Co., Ltd.Enrollment456AtherosclerosisCoronary Artery Disease

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This study is designed to evaluate the efficacy and safety of intravenously administered YN001 in patients diagnosed with coronary atherosclerosis, who are receiving background therapy for cardiovascular (CV) risk factors management.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Ying Chen, PhD
Beijing Inno Medicine Co., Ltd.
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

56 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia

Cannopy Clinical Research
Penrith, New South Wales, Australia
Recruiting
Core Research Group Pty Ltd.
Brisbane, Queensland, Australia
Recruiting
Canopy Clinical Research
Altona N., Victoria, Australia
Recruiting

Canada

St. Boniface Hospital
Winnipeg, Manitoba, Canada
Not, yet, recruiting
London Health Sciences Centre
London, Ontario, Canada
Not, yet, recruiting
North York Diagnostic and Cardiac Centre
North York, Ontario, Canada
Not, yet, recruiting
St. Michael'S Hospital
Toronto, Ontario, Canada
Not, yet, recruiting
Cardiac Clinic
Vaughan, Ontario, Canada
Not, yet, recruiting
Toronto General Hospital - University Health Network
Toronto, Toronto, Canada
Not, yet, recruiting

China

the First Affiliated Hospital of Anhui Medical Unversity
Hefei, An, China
Recruiting
Anhui Provincial Hospital
Hefei, Anhui, China
Chao Gao, MDKangyu Chen, MD
Recruiting
Anzhen Hospital
Beijing, Beijing Municipality, China
Yuyang Liu, MD
Recruiting
Beijing Jishuitan Hospital
Beijing, Beijing Municipality, China
Qingwei Ji, MDWei Liu, MD
Recruiting
Beijing Luhe Hospital
Beijing, Beijing Municipality, China
Not, yet, recruiting
Fujian Medical University Union Hospital
Fuzhou, Fujian, China
Mingfang Ye, MDZhaoyang Chen, MD
Recruiting
the Second Hospital & Clinical Medical School Lanzhou University
Lanzhou, Gansu, China
Recruiting
Guangdong Provincial People'S Hospital
Guangzhou, Guangdong, China
Not, yet, recruiting
Daqing People'S Hospital
Daqing, Heilongjiang, China
Not, yet, recruiting
the First Affiliated Hospital of Harbin Medical University
Harbin, Heilongjiang, China
Lu Fu, MDYongtai Gong, MD
Recruiting
Zhongnan Hospital of Wuhan University
Wuhan, Hubei, China
Xiaorong Hu, MD
Recruiting
the Second Xiangya Hospital Fo Central South University
Changsha, Hunan, China
Not, yet, recruiting
the First Hospital of Jilin University
Changchun, Jilin, China
Qian Tong, MD
Recruiting
the People'S Hospital of Liaoning Province
Shenyang, Liaoning, China
Ying Liu, MD
Recruiting
Shaanxi Provincial People'S Hospital
Xi'an, Shaanxi, China
Recruiting
Central Hospital Affiliated To Shandong First Medicial University
Jinan, Shandong, China
Recruiting
Fudan University-Zhongshan Hospital
Shanghai, Shanghai Municipality, China
Junbo Ge, MDYuxiang Dai, MD
Recruiting
Renji Hospital Shanghai Jiaotong University School of Medicine
Shanghai, Shanghai Municipality, China
Jun Bu, MD
Recruiting
Sichuan Provincial People'S Hospital
Chengdu, Sichuan, China
Not, yet, recruiting
West China Hospital of Sichuan University
Chengdu, Sichuan, China
Yong He, MD
Recruiting
the Second Hospital of Tianjin Medical University
Tianjin, Tianjin Municipality, China
Tong Liu, MD
Recruiting
Tianjin People'S Hospital
Tianjin, Tianjin Municipality, China
Zhuhua Yao, MD
Recruiting
Zhejiang Provincial People'S Hospital
Hangzhou, Zhejiang, China
Not, yet, recruiting
the First Affiliated Hospital of Soochow University
Suzhou, Zhejiang, China
Not, yet, recruiting
the 2nd Affiliated Hospital and Yuying Children'S Hospital of Wmu
Wenzhou, Zhejiang, China
Not, yet, recruiting

United States

Heart Center Research, Llc
Huntsville, Alabama, United States
Not, yet, recruiting
Thrive Clinical Research Group, Llc
Covina, California, United States
Not, yet, recruiting
Clinical Trials Research
Lincoln, California, United States
Not, yet, recruiting
University of California Irvine Medical Center - Cardiovascular Center
Los Alamitos, California, United States
Not, yet, recruiting
Stanford Health Care General Cardiology
Stanford, California, United States
Not, yet, recruiting
Lundquist Institute for Biomedical Innovation at Harbor-Ucla Medical Center
Torrance, California, United States
Recruiting

16 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

YN001/Placebo 0mgYN001/Placebo 20mgYN001/Placebo 40mg

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Jul 2026
Primary completion: 31 Jul 2027
Completion: 31 Mar 2029
Last update posted: 27 Oct 2026
Registered enrollment: 456
Registry id: NCT07521007

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.