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Clinical trialNCT07528690Not, yet, recruitingPhase 2Interventional

Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE)

SponsorVA Office of Research and DevelopmentEnrollment162CirrhosisHepatic Encephalopathy
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The goal of this clinical trial is to find out whether changing the microbes in the bowels of Veterans with cirrhosis and hepatic encephalopathy (a condition that affects the brain as a result of liver problems) using capsules made from microbes from healthy people can prevent future episodes of hepatic encephalopathy.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

3 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Cerc (visn1, West Haven, Ct)

    West Haven, Connecticut, United States

  • Va North Texas Health Care System Dallas Va Medical Center, Dallas, Tx

    Dallas, Texas, United States

  • Richmond Va Medical Center, Richmond, Va

    Richmond, Virginia, United States

    Jasmohan S. Bajaj, MD MS →

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Microbiota transplant therapy capsules
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
30 Oct 2026
Primary completion
31 Oct 2030
Completion
3 Mar 2031
Last update posted
14 Apr 2026
Registered enrollment
162
Registry id
NCT07528690
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.