Clinical trialNCT07555483RecruitingPhase 3Interventional

A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)

SponsorGrifols Therapeutics LLCEnrollment40Alpha 1 Antitrypsin Deficiency

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

19 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Denmark

Vijle Sygeheus
Vejle, Denmark
Ole Hilberg
Recruiting

Ireland

Beaumont Hospital
Dublin, Ireland
McElvaney Noel Gerard
Not, yet, recruiting

Netherlands

Leiden University Medical Center
Leiden, Netherlands
Emily Van't Wout
Not, yet, recruiting

Poland

Instytut Gruzlicy I Charób Pluc
Warsaw, Poland
Joana Chorostowska
Not, yet, recruiting

Portugal

Unidade Local de Saúde Do Alto Ave
Guimarães, Portugal
Caterina Guimaraes
Recruiting
Unidade Local de Saúde Loures-Odivelas
Loures, Portugal
Martin Teresa
Recruiting

Spain

Hospital Clinico San Carlos
Madrid, Spain
Juan Rodríguez Hermosa
Not, yet, recruiting
Hospital Álvaro Cunqueiro
Vigo, Spain
María Torres-Durán
Recruiting

Sweden

Skane University Hospital
Malmö, Sweden
Hanan Tanash
Recruiting

United States

University of Alabama at Birmingham
Birmingham, Alabama, United States
J. Michael Wells, MD
Not, yet, recruiting
Pulmonary Associates
Phoenix, Arizona, United States
Da-Wei Liao, MD
Not, yet, recruiting
Mayo Clinic
Scottsdale, Arizona, United States
Garrett Ashley, MD
Not, yet, recruiting
Ucla
Los Angeles, California, United States
Igor Barjaktarevic, MD, PhD
Not, yet, recruiting
University of Florida
Gainesville, Florida, United States
Jorge Lascano, MD
Not, yet, recruiting
University of Miami
Miami, Florida, United States
Michael Campos, MD
Not, yet, recruiting
Mayo Clinic
Rochester, Minnesota, United States
Megan Dulohery-Scrodin, MD
Not, yet, recruiting
Cleveland Clinic
Cleveland, Ohio, United States
Umur Hatipoglu, MD
Not, yet, recruiting
Medical University of South Carolina
Charleston, South Carolina, United States
Charlie Strange, MD
Not, yet, recruiting
Ut Southwestern Medical Center
Dallas, Texas, United States
Carlos Cardenas, MD
Not, yet, recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 5 May 2026
Primary completion: 30 Sept 2027
Completion: 30 Sept 2027
Last update posted: 1 Jun 2026
Registered enrollment: 40
Registry id: NCT07555483

Cross-registrations

EU-CTR / CTIS (EudraCT)2025-522792-29-00

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.