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Clinical trialNCT07579364Enrolling, by, invitationObservational

Outcomes Tracking in Unilateral Vocal Fold Paralysis (UVFP) and Atrophy After Medialization Laryngeal Surgery

SponsorUniversity of California, San FranciscoEnrollment500Unilateral Vocal Cord ParalysisVocal Cord Atrophy
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The goal of this observational study is to learn about the long-term outcomes of Laryngeal Framework Surgery (LFS) in patients with Unilateral Vocal Fold Paralysis (UVFP) or Vocal Fold Atrophy (VFA). The main questions it aims to answer are: * Whether LFS technique (implant material, addition of arytenoid adduction) is associated with differences in outcomes such as complication rate, duration of surgery, hospital stay length, and quality of voice post-surgery. * Whether UVFP or VFA diagnosis is associated with differences in outcomes such as complication rate, duration of surgery, hospital stay length, and quality of voice post-surgery. Participants who are determined by their clinician to need LFS for their UVFP or VFA will undergo the procedure, attend follow-up appointments, and complete surveys about their voice and swallowing ability as they would as part of their regular medical care.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of California, San Diego

    La Jolla, California, United States

  • University of Southern California

    Los Angeles, California, United States

  • University of California, San Francisco

    San Francisco, California, United States

  • University of Miami

    Miami, Florida, United States

  • Massachusetts Eye and Ear Infirmary

    Boston, Massachusetts, United States

  • Washington University in St. Louis

    St Louis, Missouri, United States

  • Wake Forest University

    Winston-Salem, North Carolina, United States

  • University of Cincinnati

    Cincinnati, Ohio, United States

  • Ohio State University

    Columbus, Ohio, United States

  • Medical University of South Carolina

    Charleston, South Carolina, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
28 Oct 2025
Primary completion
31 Jan 2028
Completion
31 Jan 2028
Last update posted
12 May 2026
Registered enrollment
500
Registry id
NCT07579364

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.