Clinical trialNCT07589595RecruitingPhase 2Interventional

A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)

SponsorEli Lilly and CompanyEnrollment350AmyloidCognitive DysfunctionLewy Body DiseaseSynucleinopathies

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The main purpose of this study is to evaluate whether treatment with donanemab slows the progression of cognitive (how we think, learn, remember, pay attention, and make decisions) and functional (how we are able to perform daily activities) decline. For each participant, the study will last one and a half years.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 8 AM - 8 PM Eastern time (UTC/GMT - 5 hours, EST)
Eli Lilly and Company
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

71 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Japan

Memory Clinic Ochanomizu
Bunkyō City, Japan
Takashi Asada
Not, yet, recruiting
Shonan Keiiku Hospital
Fujisawa, Japan
Yasuo Terayama
Not, yet, recruiting
Hyogo Prefectural Harima-Himeji General Medical Center
Himeji, Japan
Kenichi Shimada
Not, yet, recruiting
Inage Neurology and Memory Clinic
Inage, Japan
Yasumasa Yoshiyama
Not, yet, recruiting
Nippon Medical School Musashi Kosugi Hospital
Kawasaki, Japan
Kentaro Suzuki
Not, yet, recruiting
St. Marianna University Hospital
Kawasaki, Japan
Koji Kasanuki
Not, yet, recruiting
Kobe University Hospital
Kobe, Japan
Hisatomo Kowa
Not, yet, recruiting
Katayama Medical Clinic
Kurashiki, Japan
Sadao Katayama
Recruiting
Juntendo Tokyo Koto Geriatric Medical Center
Kōtoku, Japan
Kenya Nishioka
Not, yet, recruiting
Nagoya Ekisaikai Hospital
Nagoya, Japan
Tomotsugu Kaga
Not, yet, recruiting
Nagoya University Hospital
Nagoya, Japan
Masahisa Katsuno
Not, yet, recruiting
the University of Osaka Hospital
Suita, Japan
Yuto Satake
Not, yet, recruiting
Tachikawa Hospital
Tachikawa, Japan
Hidenori Hattori
Not, yet, recruiting
Memory Clinic Toride
Toride, Japan
Youshun Boku
Not, yet, recruiting
Yokohama Minami Kyosai Hospital
Yokohama, Japan
Shigeru Koyano
Not, yet, recruiting
Oita University Hospital
Yufu, Japan
Noriyuki Kimura
Not, yet, recruiting
Tokyo Metropolitan Institute for Geriatrics and Gerontology
tabashi City, Japan
Atsushi Iwata
Not, yet, recruiting
National Center for Geriatrics and Gerontology
Ōbu, Japan
Kazunori Imai
Not, yet, recruiting

South Korea

Gangnam Severance Hospital, Yonsei University Health System
Gangnam-gu, South Korea
Hanna Cho
Not, yet, recruiting
Inha University Hospital
Incheon, South Korea
Seong Hye Choi
Not, yet, recruiting
Ewha Womans University Mokdong Hospital
Seoul, South Korea
Geon Ha Kim
Not, yet, recruiting
Hanyang University Seoul Hospital
Seoul, South Korea
Hee-Jin Kim
Not, yet, recruiting
Konkuk University Medical Center
Seoul, South Korea
Seol-Heui Han
Not, yet, recruiting

Taiwan

New Taipei Municipal Tucheng Hospital
New Taipei City, Taiwan
Jung Lung Hsu
Not, yet, recruiting
Taipei Medical University Shuang Ho Hospital
New Taipei City, Taiwan
Chaur-Jong Hu
Not, yet, recruiting
National Cheng Kung University Hospital
Tainan, Taiwan
MingChyi Pai
Not, yet, recruiting
National Taiwan University Hospital
Taipei, Taiwan
Cheng-Hsuan Li
Not, yet, recruiting
Taipei Veterans General Hospital
Taipei, Taiwan
Jong-Ling Fuh
Not, yet, recruiting
Chang Gung Medical Foundation-Linkou Branch
Taoyuan, Taiwan
WEI-MIN HO
Not, yet, recruiting

United States

Trialsphere Corp
Chandler, Arizona, United States
Hemant Pandey
Recruiting
Honorhealth Research Institute
Scottsdale, Arizona, United States
Todd Levine
Not, yet, recruiting
Profound Research Llc
Carlsbad, California, United States
Benjamin Frishberg
Recruiting
Irvine Clinical Research
Irvine, California, United States
Edward Zamrini
Recruiting
Ucsd - Altman Clinical and Translational Research Institute (actri)
La Jolla, California, United States
Stephanie Lessig
Not, yet, recruiting
Stanford Neuroscience Health Center
Palo Alto, California, United States
Irina Skylar-Scott
Not, yet, recruiting
Cenexel Rocky Mountain Clinical Research
Englewood, Colorado, United States
Meagen Salinas
Not, yet, recruiting
Ki Health Partners, Llc, Dba New England Institute for Clinical Research
Stamford, Connecticut, United States
Peter McAllister
Not, yet, recruiting
Jem Research Institute
Atlantis, Florida, United States
Linda Pao
Recruiting
Vin - Aventura
Aventura, Florida, United States
Jonathan Cross
Recruiting
Brain Matters Research
Delray Beach, Florida, United States
Paayal Patel
Recruiting

31 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Donanemab →Placebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 20 May 2026
Primary completion: 31 Aug 2028
Completion: 31 Aug 2028
Last update posted: 6 Aug 2026
Registered enrollment: 350
Registry id: NCT07589595

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.