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Clinical trialNCT07601295Not, yet, recruitingPhase 2Interventional

Tiprelestat Versus Placebo When Added to Standard of Care for the Treatment of Pulmonary Arterial Hypertension (PAH)

SponsorStanford UniversityEnrollment90Pulmonary Arterial Hypertension (PAH)
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The primary objective of this study is to compare the efficacy, safety, and tolerability of tiprelestat plus Standard of Care (SOC) compared with placebo plus SOC in patients with World Health Organization (WHO) functional class II-IV pulmonary arterial hypertension (PAH).
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

10 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • the University of Arizona / Banner University Medical Center

    Tucson, Arizona, United States

  • University of California, San Francisco

    San Francisco, California, United States

  • Stanford University

    Stanford, California, United States

  • University of Colorado (ucd) Anschutz

    Aurora, Colorado, United States

  • Harvard University / Brigham and Women'S Hospital

    Boston, Massachusetts, United States

  • Duke University

    Durham, North Carolina, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, United States

  • Brown University/rhode Island Hospital

    Providence, Rhode Island, United States

  • University of Texas Southwestern

    Dallas, Texas, United States

  • University of Washington

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

PlaceboTiprelestat
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Jul 2026
Primary completion
28 Feb 2030
Completion
31 Mar 2030
Last update posted
22 May 2026
Registered enrollment
90
Registry id
NCT07601295
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.