Clinical trialNCT07610876CompletedInterventional

Autologous Demineralized Dentin Graft With or Without Melatonin for Immediate Implant Osseointegration

SponsorSuez Canal UniversityEnrollment30Dental ImplantsImmediate Implant PlacementOsseointegration

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This randomized clinical study aims to evaluate the effect of autologous demineralized dentin graft (ADDG) with or without melatonin gel on the osseointegration of immediately placed dental implants in the maxillary premolar region. Thirty patients requiring extraction and immediate implant placement will be randomly allocated into two groups. Clinical and radiographic outcomes including implant stability, peri-implant probing depth, modified bleeding index, marginal bone loss, buccal bone thickness, and bone density will be evaluated over a 9-month follow-up period.

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Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Abd El Fattah ELSaid Attia, B.S.D
B.S.D
Principal Investigator
clinicaltrials.gov ↗
Hany Kamel Shalaby
Professor of Oral Medicine and Periodontology, Dean Faculty of Dentistry
Study Chair
clinicaltrials.gov ↗
Rasha El-Sayed Afifi
Lecturer of Oral Medicine and Periodontology
Study Director
clinicaltrials.gov ↗
Shaima Mohammed Morsy
Assistant Professor of Oral Medicine and Periodontology
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Egypt

Suez Canal University, Faculty of Dentistry
Ismailia, Egypt

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Melatonin gel

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 11 Aug 2025
Primary completion: 10 Oct 2026
Completion: 15 Oct 2026
Last update posted: 22 Oct 2026
Registered enrollment: 30
Registry id: NCT07610876

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 11 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.