Clinical trialNCT07624279Not, yet, recruitingPhase 2Interventional

nVNS, CBD, and SoC for Persistent Post-Traumatic Headache

SponsorAmerican Society of Pain and Neuroscience, Inc.Enrollment80Persistent Post Traumatic Headache

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

Do cannabidiol (CBD) or vagus nerve stimulation reduce the frequency of persistent post-traumatic headache more than traditional oral headache medications?

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Erika A Petersen, MD
University of Arkansas
Principal Investigator
clinicaltrials.gov ↗
Nathaniel M Schuster, MD
University of California, San Diego
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

8 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Mayo Clinic
Scottsdale, Arizona, United States
Natalie Strand, MD
Kerlan-Jobe Orthopaedic Institute
Los Angeles, California, United States
Vernon Williams, MD
International Spine, Pain & Performance Center
Washington D.C., District of Columbia, United States
Mehul Desai, MD
Florida Spine & Pain Specialists
Tampa, Florida, United States
Nomen Azeem, MD
University of Kansas Medical Center
Kansas City, Kansas, United States
Dawood Sayed, MD
Premier Pain Center
Shrewsbury, New Jersey, United States
Sean Li, MD
University Hospitals Cleveland Medical Center
Cleveland, Ohio, United States
Melinda Lawrence, MD
Allegheny General Hospital
Pittsburgh, Pennsylvania, United States
Boyle Cheng, PhDPatrick DeMeo, MDPraveer Vyas, PhD

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Cannabidiol →Standard of Care

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 Jun 2026
Primary completion: 31 Jul 2027
Completion: 1 Jul 2028
Last update posted: 3 Jun 2026
Registered enrollment: 80
Registry id: NCT07624279

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.