findmyKOL
Clinical trialNCT07645300Not, yet, recruitingPhase 2Interventional

LOw DosE Spironolactone, chlorThAlidone oR Combination in CKD Trial

SponsorVA Office of Research and DevelopmentEnrollment160Chronic Kidney Disease, 3B and 4Hypertension Treated With Antihypertensive Drugs
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this research is to gather information on the safety and effectiveness of spironolactone and chlorthalidone for treatment of high blood pressure in patients with moderate to advanced CKD. Both drugs have been approved by the Food and Drug Administration (FDA) for the treatment of high blood pressure since 1960.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Phase 2A ChlorthalidonePhase 2A Chlorthalidone + SpironolactonePhase 2A SpironolactonePhase 2B Chlorthalidone LD + Spironolactone LD
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
1 Oct 2026
Primary completion
31 Mar 2032
Completion
30 Jun 2032
Last update posted
12 Jun 2026
Registered enrollment
160
Registry id
NCT07645300
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.