Clinical trialNCT07652580RecruitingObservational

Toxin Exposure and Immune Dysregulation in Non-Hodgkin Lymphoma

SponsorHenry M. Jackson Foundation for the Advancement of Military MedicineEnrollment300B-cell LymphomaImmune DysregulationLymphoma Non-HodgkinNon-Hodgkin Lymphoma

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The goal of this observational cohort study is to learn how toxin and occupational exposures, germline genetic variation, and immune dysregulation relate to B-cell non-Hodgkin lymphoma among active-duty service members and other Military Health System beneficiaries. The main questions are whether specific exposures and germline variants are associated with B-cell NHL subtype, immune dysfunction, and clinical outcomes. Participants will complete exposure and medical-history surveys, provide biospecimens for immune and genomic testing, and may be followed annually for up to 3 years.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Christin Destefano
Uniformed Services University of the Health Sciences
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

3 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Uniformed Services University of the Health Sciences
Bethesda, Maryland, United States
Active, not recruiting
Walter Reed National Military Medical Center
Bethesda, Maryland, United States
Jeremy Perkins, MD, FACP, COL, US Army (ret)
Recruiting
Naval Medical Center Portsmouth
Portsmouth, Virginia, United States
Active, not recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 1 May 2025
Primary completion: 1 May 2028
Completion: 1 May 2028
Last update posted: 3 Sept 2026
Registered enrollment: 300
Registry id: NCT07652580

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 4 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.