Clinical trialNCT07689227Not, yet, recruitingInterventional

Closed-Loop Vagus Nerve Stimulation (CLV) for Recovery of Gait After Spinal Cord Injury (SCI)

SponsorThe University of Texas at DallasEnrollment20Functional MobilityGaitLower Limb FunctionsMobility ImpairmentReduced Physical ActivitySpinal Cord Injury (SCI)+1 more conditions

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to evaluate the safety, feasibility, and preliminary effectiveness of the ReWire system, which delivers vagus nerve stimulation (VNS) paired with lower limb rehabilitation to improve gait in individuals with mobility impairments resulting from chronic, incomplete spinal cord injury (SCI).

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a FindMyKOL profile link to it; the rest are shown as registered.

Chad Swank, PhD
Spaulding Rehabilitation Hospital, Mass General Brigham
Principal Investigator
clinicaltrials.gov ↗
Jane Wigginton, MD
The University of Texas at Dallas
Principal Investigator
clinicaltrials.gov ↗
Michael Foreman, MD
Urgent Surgery Associates, PA
Principal Investigator
clinicaltrials.gov ↗
Rita Hamilton, DO
Baylor University Medical Center (BUMC)
Principal Investigator
clinicaltrials.gov ↗
Robert Rennaker, PhD
The University of Texas at Dallas
Principal Investigator
clinicaltrials.gov ↗
Seth Hays, PhD
The University of Texas at Dallas
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

4 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Spaulding Rehabilitation Hospital, Mass General Brigham
Boston, Massachusetts, United States
Chad Swank, PhD
Baylor University Medical Center (bumc)
Dallas, Texas, United States
Rita Hamilton, DO
Urgent Surgery Associates, Pa
Dallas, Texas, United States
Michael Foreman, MD
Texas Biomedical Device Center
Richardson, Texas, United States
Jane Wigginton, MDRobert Rennaker, PhD

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 30 Sept 2026
Primary completion: 31 Dec 2028
Completion: 31 Dec 2028
Last update posted: 27 Jul 2026
Registered enrollment: 20
Registry id: NCT07689227

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 11 Nov 2026. Registry facts are shown as registered by the study sponsor; FindMyKOL does not interpret them.