Clinical trialNCT07778459RecruitingObservational

Expanding HOPE Liver

SponsorNational Institute of Allergy and Infectious Diseases (NIAID)Enrollment80HIV InfectionLiver Transplant

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a prospective, multicenter clinical study. The objective is to determine whether a liver transplant from a deceased donor with HIV is associated with an increased risk of opportunistic infection and cancer. Adults with Human Immunodeficiency Virus (HIV) in need of a liver or simultaneous liver-kidney (SLK) transplant who meet study-specified criteria will be offered enrollment in the study. The analytic plan includes an observational cohort of liver and SLK transplant recipients from prior HOPE in Action studies.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Aaron Tobian, MD, PhD
Johns Hopkins Hospital: Transplantation
Study Chair
clinicaltrials.gov ↗
Christine Durand, MD
Johns Hopkins Hospital: Transplantation
Study ChairKOL profile →
clinicaltrials.gov ↗
Dorry Segev, MD, PhD
New York University Langone Health: Transplantation
Study Chair
clinicaltrials.gov ↗
James P Hamilton, MD
Johns Hopkins Hospital: Transplantation
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

2 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Johns Hopkins University (site #: 71119)
Baltimore, Maryland, United States
Recruiting
Icahn School of Medicine at Mount Sinai (site # 71115)
New York, New York, United States
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 15 Oct 2026
Primary completion: 31 Aug 2030
Completion: 31 Aug 2030
Last update posted: 21 Aug 2026
Registered enrollment: 80
Registry id: NCT07778459

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.