Clinical trialNCT00104949CompletedPhase 2Interventional

Trastuzumab in Treating Patients With Locally Advanced or Metastatic Synovial Sarcoma

SponsorSWOG Cancer Research NetworkEnrollment40Sarcoma

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

RATIONALE: Monoclonal antibodies, such as trastuzumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Trastuzumab may also stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. PURPOSE: This phase II trial is studying how well trastuzumab works in treating patients with locally advanced or metastatic synovial sarcoma.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Ernest C. Borden, MD
The Cleveland Clinic
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George D. Demetri, MD
Dana-Farber Cancer Institute
KOL profile →
clinicaltrials.gov ↗
Karen H. Albritton, MD
Dana-Farber Cancer Institute
clinicaltrials.gov ↗
Margaret von Mehren, MD
Fox Chase Cancer Center
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Rashmi Chugh, MD
University of Michigan Rogel Cancer Center
clinicaltrials.gov ↗
Vivien H.C. Bramwell, MB, BS, PhD, FRCP
Tom Baker Cancer Centre - Calgary
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

No facility list is in our current data snapshot for this study. The registry record on ClinicalTrials.gov ↗ carries any published locations. Why? →

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Trastuzumab →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Jul 2005
Primary completion: —
Completion: 31 Aug 2007
Last update posted: 24 Jun 2013
Registered enrollment: 40
Registry id: NCT00104949

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.