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Clinical trialNCT00125203CompletedPhase 2/PHASE3Interventional

Study of Myobloc in the Treatment of Sialorrhea (Drooling) in Patients With Amyotrophic Lateral Sclerosis (ALS)

SponsorThe University of Texas Health Science Center at San AntonioEnrollment20Amyotrophic Lateral SclerosisSialorrhea
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine the safety and efficacy of Myobloc in ALS patients who are having excessive drooling. The primary goal of the study is to determine if the patient perceives a benefit from the Myobloc in controlling excessive drooling.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

  • Carlayne E Jackson, MD

    The University of Texas Health Science Center at San Antonio

    Principal Investigator
    clinicaltrials.gov ↗
  • Charles B Simpson, MD

    The University of Texas Health Science Center at San Antonio

    Principal Investigator
    clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

2 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • University of Kansas Medical Center/neurology, 1008 Wescoe

    Kansas City, Kansas, United States

  • Carolinas Mda Neuromuscular/als Center; Carolinas Medical System; 1540 Garden Terrace

    Charlotte, North Carolina, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Botulinum toxin type B →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Jul 2003
Primary completion
—
Completion
31 Aug 2007
Last update posted
14 Mar 2012
Registered enrollment
20
Registry id
NCT00125203
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.