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Clinical trialNCT00281294TerminatedPhase 2Interventional

A Phase 2 Study to Evaluate the Safety, Tolerability, and Activity of Fontolizumab in Subjects With Active Rheumatoid Arthritis

SponsorPDL BioPharma, Inc.Enrollment40Arthritis, Rheumatoid
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To evaluate the efficacy of fontolizumab in subjects with active rheumatoid arthritis as determined by a 50% improvement of an American College of Rheumatology criteria (ACR50) response at Week 14 (Stage A of study).

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Wallace Rheumatic Study Center

    Los Angeles, California, United States

  • Stanford University Medical Center-Div. of Rheumatology

    Palo Alto, California, United States

  • Denver Arthritis Clinic

    Denver, Colorado, United States

  • Coeur D Alene Arthritis Clinic

    Coeur d'Alene, Idaho, United States

  • Rheumatology Associates Clinical Research

    Chicago, Illinois, United States

  • Justus J. Fiechtner Md Pc

    Lansing, Michigan, United States

  • the Center for Rheumatology

    Albany, New York, United States

  • Altoona Center for Clinical Research

    Duncansville, Pennsylvania, United States

  • Benaroya Research Institute at Virginia Mason

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Fontolizumab
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Dec 2005
Primary completion
—
Completion
31 Dec 2006
Last update posted
5 Aug 2008
Registered enrollment
40
Registry id
NCT00281294

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.