Clinical trialNCT00443430CompletedPhase 4Interventional

Trial of Early Aggressive Drug Therapy in Juvenile Idiopathic Arthritis

SponsorSeattle Children's HospitalEnrollment85Juvenile Chronic PolyarthritisJuvenile Idiopathic ArthritisJuvenile Rheumatoid Arthritis

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to compare two aggressive drug regimens for children with poly-juvenile idiopathic arthritis (JIA) and extended oligo JIA.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Carol A. Wallace, MD
Childrens Hospital and Regional Medical Center
Principal Investigator
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A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

15 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Stanford University Medical Center
Palo Alto, California, United States
Rady Children'S Hospital
San Diego, California, United States
University of California San Francisco Medical Center
San Francisco, California, United States
Children'S Hospital of Boston
Boston, Massachusetts, United States
Hackensack University Medical Center
Hackensack, New Jersey, United States
Schneider Children'S Hospital
New Hyde Park, New York, United States
Children'S Hospital at Montefiore
The Bronx, New York, United States
Duke University
Durham, North Carolina, United States
Cincinnati Children'S Hospital Medical Center
Cincinnati, Ohio, United States
Cleveland Clinic Foundation
Cleveland, Ohio, United States
Children'S Hospital of Columbus
Columbus, Ohio, United States
Oklahoma University Health Science Center
Oklahoma City, Oklahoma, United States
Texas Scottish Rite Hospital
Dallas, Texas, United States
University of Utah
Salt Lake City, Utah, United States
Seattle Children'S Hospital and Regional Medical Center
Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Methotrexate →Methotrexate - etanercept - prednisolone arm

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 May 2007
Primary completion: 31 Oct 2010
Completion: 31 Oct 2010
Last update posted: 31 May 2013
Registered enrollment: 85
Registry id: NCT00443430

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.