findmyKOL
Clinical trialNCT00451204CompletedPhase 2Interventional

A Combination Trial of Copaxone Plus Estriol in Relapsing Remitting Multiple Sclerosis (RRMS)

SponsorUniversity of California, Los AngelesEnrollment158Relapsing Remitting Multiple Sclerosis
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a double-blinded, placebo controlled study of estriol pills versus placebo pills in relapsing remitting multiple sclerosis. The study treatment will be an added on to Copaxone injections in all subjects. The primary outcome measure is a reduction in relapses.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

16 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • Montreal Neurological Institute

    Montreal, Canada

United States
  • Mayo Clinic

    Scottsdale, Arizona, United States

  • University of California, Los Angeles

    Los Angeles, California, United States

  • University of Colorado

    Aurora, Colorado, United States

  • University of Chicago

    Chicago, Illinois, United States

  • University of Kansas

    Kansas City, Kansas, United States

  • Johns Hopkins University

    Baltimore, Maryland, United States

  • University of Minnesota

    Minneapolis, Minnesota, United States

  • Washington University

    St Louis, Missouri, United States

  • Dartmouth Medical School

    Lebanon, New Hampshire, United States

  • Umdnj-Robert Wood Johnson Medical Center

    New Brunswick, New Jersey, United States

  • University of New Mexico

    Albuquerque, New Mexico, United States

  • Ohio State University

    Columbus, Ohio, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, United States

  • University of Texas Southwestern

    Dallas, Texas, United States

  • Western Institute for Biomedical Research

    Salt Lake City, Utah, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Glatiramer →EstriolPlacebo
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Mar 2007
Primary completion
31 Jul 2014
Completion
31 Jul 2014
Last update posted
16 Jun 2016
Registered enrollment
158
Registry id
NCT00451204

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.