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Clinical trialNCT01471782CompletedPhase 1/PHASE2Interventional

Clinical Study With Blinatumomab in Pediatric and Adolescent Patients With Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia

SponsorAmgen Research (Munich) GmbHEnrollment93Acute Lymphoblastic Leukemia
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine the dose of the bispecific T cell engager blinatumomab (MT103) in pediatric and adolescent patients with relapsed/refractory acute lymphoblastic leukemia (ALL) and to assess whether this dose of blinatumomab is effective.

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

30 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Austria
  • St. Anna Kinderspital

    Vienna, Austria

Canada
  • Hospital for Sick Children

    Toronto, Ontario, Canada

France
  • (chu Besancon) Hopital Saint-Jaques

    Besançon, France

  • Hôpital de la Timone (enfants)

    Marseille, France

  • Hopital Robert Debré (ap-Hp)

    Paris, France

Germany
  • Charité Campus Virchow Klinikum, Otto-Heubner-Centrum (ohc) Für Kinder- Und Jugendmedizin

    Berlin, Germany

  • Universitätsklinikum Düsseldorf

    Düsseldorf, Germany

  • Universitätsklinikum Essen

    Essen, Germany

  • Klinikum Der Johann Wolfgang Goethe-Universität Frankfurt/main

    Frankfurt am Main, Germany

  • Universitätsklinikum Hamburg-Eppendorf

    Hamburg, Germany

  • Medizinische Hochschule Hannover

    Hanover, Germany

  • Universitätsklinikum Schleswig-Holstein Campus Kiel

    Kiel, Germany

  • Klinikum Der Universität München, Dr. Von Haunersches Kinderspital

    München, Germany

  • Universitätsklinik Für Kinder- Und Jugendmedizin Tübingen

    Tübingen, Germany

  • Universitätsklinikum Würzburg

    Würzburg, Germany

Italy
  • University of Milano-Bicocca, Hospital San Gerardo

    Monza, Italy

  • Dipartimento Della Donna E del Bambino

    Padova, Italy

  • the Bambino Gesù Children'S Hospital

    Rome, Italy

Netherlands
  • Erasmus Mc, Sophia Children'S Hospital

    Rotterdam, Netherlands

United States
  • Children'S Hospital Denver

    Aurora, Colorado, United States

  • Children'S Healthcare of Atlanta at Egleston

    Atlanta, Georgia, United States

  • Washington University

    St Louis, Missouri, United States

  • Memorial Sloan Kettering

    New York, New York, United States

  • Cincinnati Children'S Hospital Medical Center

    Cincinnati, Ohio, United States

  • Children'S Hospital of Philadelphia

    Philadelphia, Pennsylvania, United States

  • St Jude Children'S Research Hospital

    Memphis, Tennessee, United States

  • Ut Southwestern Medical Center

    Dallas, Texas, United States

  • Texas Children'S Cancer Center/ Baylor

    Houston, Texas, United States

  • Primary Children'S Medical Center

    Salt Lake City, Utah, United States

  • Seattle Children'S Hospital

    Seattle, Washington, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
31 Jan 2012
Primary completion
31 Aug 2014
Completion
31 May 2016
Last update posted
8 Feb 2017
Registered enrollment
93
Registry id
NCT01471782

Cross-registrations

EU-CTR / CTIS (EudraCT)2010-024264-18

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.