A Phase 1 Dose Escalation and Expanded Cohort Study of EPZ-5676 in the Treatment of Pediatric Patients With Relapsed/Refractory Leukemias Bearing a Rearrangement of the MLL Gene
Summary
The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →
Investigators
The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.
- Cynthia Wetmore, MD PhD
Emory Children's Healthcare of Atlanta
Principal Investigator - Jim A Whitlock, MD
Hospital of Sick Kids
Principal Investigator - Lewis Silverman, MD
Dana Farber
Principal Investigator - Lia Gore, MD
Children's Hospital Colorado
Principal Investigator - Maureen O'Brien, MD
Children's Hospital Medical Center, Cincinnati
Principal Investigator - Mignon Loh, MD
University of California, San Francisco
Principal Investigator - Neal Shukla, MD
Memorial Sloan Kettering Cancer Center
Principal Investigator - Pat Brown, MD
Johns Hopkins University
Principal Investigator - Paul Gaynon, MD
Children's Hospital Los Angeles
Principal Investigator - Todd Cooper, MD
Seattle Children's Hospital
Principal Investigator
A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.
Sites
9 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.
- the Hospital for Sick Kids
Toronto, Ontario, Canada
- Childrens Hospital Los Angeles
Los Angeles, California, United States
- University of California San Francisco Medical Center-Parnassus
San Francisco, California, United States
- Children'S Hospital Colorado
Aurora, Colorado, United States
- Emory Children'S Healthcare of Atlanta
Atlanta, Georgia, United States
- Johns Hopkins University
Baltimore, Maryland, United States
- Dana Farber Cancer Institute
Boston, Massachusetts, United States
- Memorial Sloan Kettering Cancer Center
New York, New York, United States
- Cincinnati Children'S Hospital Medical Center
Cincinnati, Ohio, United States
Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.
Drugs studied
No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →
Registration & key dates
Registry attributes as recorded on the ClinicalTrials.gov study record.
- Start
- 31 May 2014
- Primary completion
- 31 May 2016
- Completion
- 30 Jun 2016
- Last update posted
- 18 Jun 2023
- Registered enrollment
- 18
- Registry id
- NCT02141828
Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.