Clinical trialNCT02238483CompletedPhase 2Interventional

A Phase IIa Study to Investigate the Efficacy and Safety of AZD7624 in Chronic Obstructive Pulmonary Disease (COPD) Patients While on Maintenance Therapy

SponsorAstraZenecaEnrollment213Chronic Obstructive Pulmonary Disease COPD

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this study is to determine whether AZD7624 can reduce acute Chronic Obstructive Pulmonary Disease (COPD) exacerbations in patients on COPD maintenance therapy with a history of frequent acute exacerbations.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Barry Make, MD, FCCP, FACVPR
National Jewish Health, Denver, United States
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗
Naimish Patel, MD, PhD
AstraZeneca R&D Boston
Study Director
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

41 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Argentina

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Buenos Aires, Argentina
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CABA, Argentina
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Ciudad Autónoma de Bs. As., Argentina
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Quilmes, Argentina
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San Miguel de Tucumán, Argentina

Chile

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Santiago, Chile
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Santiago, Chile
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Talca, Chile
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Talcahuano, Chile

Netherlands

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Assen, Netherlands
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Heerlen, Netherlands
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Nijmegen, Netherlands
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Zutphen, Netherlands

Peru

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Lima, Peru
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Lima, Peru

South Africa

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Cape Town, South Africa
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Johannesburg, South Africa
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Johannesburg, South Africa
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Mount Edgecombe, South Africa
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Parktown West, South Africa
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eManzimtoti, South Africa

United States

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Los Angeles, California, United States
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Torrance, California, United States
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Denver, Colorado, United States
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Hialeah, Florida, United States
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Miami, Florida, United States
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Pembroke Pines, Florida, United States
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Atlanta, Georgia, United States
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Blue Ridge, Georgia, United States
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Baltimore, Maryland, United States
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St Louis, Missouri, United States
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Larchmont, New York, United States
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Charlotte, North Carolina, United States
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Wilmington, North Carolina, United States
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Akron, Ohio, United States
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Dayton, Ohio, United States
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Erie, Pennsylvania, United States
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Gaffney, South Carolina, United States
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Greenville, South Carolina, United States
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Rock Hill, South Carolina, United States

1 more site on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

AZD7624 1.0 mgPlacebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 28 Oct 2014
Primary completion: 4 Apr 2016
Completion: 4 Apr 2016
Last update posted: 24 May 2018
Registered enrollment: 213
Registry id: NCT02238483

Cross-registrations

EU-CTR / CTIS (EudraCT)2014-001053-16

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.