Clinical trialNCT06404073CompletedInterventional

RECOVER-ENERGIZE Platform Protocol_Appendix B (Structured Pacing (PEM))

SponsorDuke UniversityEnrollment300Long COVIDLong Covid-19Long Covid19

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a platform protocol designed to be flexible so that it is suitable for a range of interventions and settings within diverse health care systems and community settings with incorporation into clinical COVID-19 management programs and treatment plans if results achieve key study outcomes. This protocol is a prospective, multi-center, multi-arm, randomized, controlled platform trial evaluating interventions to address and improve exercise intolerance and post-exertional malaise (PEM) as manifestations of Post-Acute Sequelae of SARS-CoV-2 Infection (PASC). The focus of this protocol is to assess interventions that can improve exercise capacity, daily activities tolerance, and quality of life in patients with PASC.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Barry Make, MD
National Jewish Health
Study ChairKOL profile →
clinicaltrials.gov ↗
Gary M Felker, MD
Duke Clinical Research Institute
Study Chair
clinicaltrials.gov ↗
Janna Friedly, MD, MPH
University of Washington
Study Chair
clinicaltrials.gov ↗
Lucinda Bateman, MD
Bateman Horne Center
Study Chair
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

All Sites Listed Under Nct06404047
Durham, North Carolina, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 17 Jul 2024
Primary completion: 18 Aug 2025
Completion: 17 Nov 2025
Last update posted: 6 May 2026
Registered enrollment: 300
Registry id: NCT06404073

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.