Clinical trialNCT03887715RecruitingInterventional

A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression

SponsorLivaNovaEnrollment6,800Treatment Resistant Depression

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Charles Conway, MD
Washington University School of Medicine
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

101 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama at Birmingham
Birmingham, Alabama, United States
Matthew Macaluso, DO
Recruiting
Uab Huntsville Regional Medical Center
Huntsville, Alabama, United States
Richard Shelton
Recruiting
Access Multi Specialty Medical Clinic, Inc
Burlingame, California, United States
Terminated
Cmb Clinical Trials
Colton, California, United States
Withdrawn
Atp Clinical Research, Inc.
Costa Mesa, California, United States
Gustavo Alva, MD
Recruiting
Kaizen Brain Center
La Jolla, California, United States
Mohammed Ahmed, MD
Recruiting
Keck Hospital of Usc
Los Angeles, California, United States
Ashraf Elmashat, MD
Recruiting
University of California San Diego
San Diego, California, United States
Active, not recruiting
Sf-Care, Inc.
San Rafael, California, United States
Terminated
Syrentis Clinical Research
Santa Ana, California, United States
Withdrawn
Mindful Behavioral Health
Boca Raton, Florida, United States
Ivan Cichowicz, MD
Recruiting
Sunrise Research Institute
Boca Raton, Florida, United States
Terminated
Medycal Research, Inc
Brooksville, Florida, United States
Terminated
Galiz Research Llc
Hialeah, Florida, United States
Jose Gamez, MD
Recruiting
Flourish Research - St. Augustine
Jacksonville, Florida, United States
Heather Luing
Recruiting
Florida Behavioral Psych
Largo, Florida, United States
Ashok Patel, MD
Recruiting
Segal Trials Corporate
Lauderhill, Florida, United States
Withdrawn
Central Miami Medical Institute, Llc
Miami, Florida, United States
Withdrawn
Clintex Research Group, Inc.
Miami, Florida, United States
Terminated
Research Center of Florida, Inc
Miami, Florida, United States
Withdrawn
Ocean Blue Medical Research Center
Miami Springs, Florida, United States
Withdrawn
Apg Research, Llc
Orlando, Florida, United States
Morteza Nadjafi, MD
Recruiting
Florida Center for Tms
Orlando, Florida, United States
Terminated
Millenia Psychiatry & Research, Inc
Orlando, Florida, United States
Withdrawn
Nova Psychiatry Inc.
Orlando, Florida, United States
David Medina, MD
Recruiting
Quantum Laboratories Inc.
Pompano Beach, Florida, United States
Terminated
Dtms Center, Lcc
Royal Palm Beach, Florida, United States
Terminated
Florida Center for Tms
Saint Augustine, Florida, United States
Terminated
Iptb Clinical Research
Tampa, Florida, United States
Jamie Winderbaum Fernandez
Recruiting
K2 Medical Research
Tampa, Florida, United States
Kelley Wilson, MD
Recruiting
Stedman Clinical Trials
Tampa, Florida, United States
Terminated
Psychiatric Specialty Center
West Palm Beach, Florida, United States
Terminated
Emory University
Atlanta, Georgia, United States
Patricio Riva Posse, MD
Recruiting
Medical College of Georgia, Augusta University
Augusta, Georgia, United States
Boadie Dunlop, MD
Recruiting
Pact Atlanta Llc
Decatur, Georgia, United States
Terminated
Iact Health
Grayson, Georgia, United States
Withdrawn
Psych Atlanta
Marietta, Georgia, United States
Michael Banov, MD
Recruiting
Pearl Health Clinic
Ammon, Idaho, United States
Withdrawn
Rush University Medical Center
Chicago, Illinois, United States
John Zajecka
Recruiting
Joliet Center for Clinical Research
Joliet, Illinois, United States
Terminated

61 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 26 Sept 2019
Primary completion: 28 Feb 2028
Completion: 31 Dec 2030
Last update posted: 15 Jun 2026
Registered enrollment: 6,800
Registry id: NCT03887715

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.