Clinical trialNCT04112641Active, not recruitingPhase 2Interventional

NIAGEN and Persistent Chemotherapy-Induced Peripheral Neuropathy

SponsorDonna Hammond, PhDEnrollment48Chemotherapy-induced Peripheral Neuropathy

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The purpose of this randomized, double-blind, placebo-controlled, parallel group phase II trial is to determine whether nicotinamide riboside (NIAGEN®, NR) can ameliorate persistent peripheral neuropathy in cancer survivors who have completed chemotherapy with taxane or platinum-complex compounds between 1 and 12 months earlier.

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Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Donna Hammond, Ph.D.
University of Iowa
Principal Investigator
clinicaltrials.gov ↗
Michael Shy, M.D.
University of Iowa
Principal Investigator
clinicaltrials.gov ↗
Mohammed Milhem, M.D.
University of Iowa
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

1 registered facility, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Donna Hammond
Iowa City, Iowa, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Nicotinamide RibosidePlacebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 19 Feb 2020
Primary completion: 28 Jun 2027
Completion: 1 Dec 2027
Last update posted: 20 Aug 2026
Registered enrollment: 48
Registry id: NCT04112641

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.