Clinical trialNCT04197687UnknownPhase 2Interventional

TPIV100 and Sargramostim for the Treatment of HER2 Positive, Stage II-III Breast Cancer in Patients With Residual Disease After Chemotherapy and Surgery

SponsorAcademic and Community Cancer Research UnitedEnrollment480Breast AdenocarcinomaStage II Breast Cancer AJCC v6 and v7Stage IIA Breast Cancer AJCC v6 and v7Stage IIB Breast Cancer AJCC v6 and v7Stage III Breast Cancer AJCC v7Stage IIIA Breast Cancer AJCC v7+2 more conditions

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Saranya Chumsri
Mayo Clinic
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

30 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Mayo Clinic in Arizona
Scottsdale, Arizona, United States
Brenda J. Ernst
Recruiting
Banner University Medical Center - Tucson
Tucson, Arizona, United States
Pavani Chalasani
Recruiting
University of Arizona Cancer Center-North Campus
Tucson, Arizona, United States
Pavani Chalasani
Recruiting
Yuma Regional Medical Center
Yuma, Arizona, United States
Withdrawn
City of Hope Comprehensive Cancer Center
Duarte, California, United States
Withdrawn
Uc San Diego Moores Cancer Center
La Jolla, California, United States
Sarah G. Boles
Not, yet, recruiting
Middlesex Hospital
Middletown, Connecticut, United States
Withdrawn
University of Florida Health Science Center - Gainesville
Gainesville, Florida, United States
Karen C. Daily
Recruiting
Mayo Clinic in Florida
Jacksonville, Florida, United States
Saranya Chumsri
Recruiting
Cleveland Clinic Florida
West Palm Beach, Florida, United States
Withdrawn
Emory University Hospital/winship Cancer Institute
Atlanta, Georgia, United States
Keerthi Gogineni
Not, yet, recruiting
Illinois Cancercare-Peoria
Peoria, Illinois, United States
Withdrawn
Carle Cancer Center Nci Community Oncology Research Program
Urbana, Illinois, United States
Withdrawn
Siouxland Regional Cancer Center
Sioux City, Iowa, United States
Withdrawn
University Medical Center New Orleans
New Orleans, Louisiana, United States
Jyotsna Fuloria
Recruiting
University of Maryland/greenebaum Cancer Center
Baltimore, Maryland, United States
Katherine H. Tkaczuk
Not, yet, recruiting
Essentia Health Nci Community Oncology Research Program
Duluth, Minnesota, United States
Withdrawn
Mayo Clinic in Rochester
Rochester, Minnesota, United States
Kathryn J. Ruddy
Recruiting
Coborn Cancer Center at Saint Cloud Hospital
Saint Cloud, Minnesota, United States
Withdrawn
Washington University School of Medicine
St Louis, Missouri, United States
Withdrawn
University of Nebraska Medical Center
Omaha, Nebraska, United States
Jairam Krishnamurthy, MD
Recruiting
Dartmouth Hitchcock Medical Center/dartmouth Cancer Center
Lebanon, New Hampshire, United States
Mary D. Chamberlin
Recruiting
Firsthealth of the Carolinas-Moore Regional Hospital
Pinehurst, North Carolina, United States
Charles S. Kuzma
Recruiting
Guthrie Medical Group Pc-Robert Packer Hospital
Sayre, Pennsylvania, United States
Withdrawn
Lexington Medical Center
West Columbia, South Carolina, United States
Withdrawn
Vanderbilt University/ingram Cancer Center
Nashville, Tennessee, United States
Vandana G. Abramson
Not, yet, recruiting
Inova Fairfax Hospital
Falls Church, Virginia, United States
Withdrawn
Marshfield Medical Center-Ec Cancer Center
Eau Claire, Wisconsin, United States
Arlene A. Gayle
Not, yet, recruiting
Saint Vincent Hospital Cancer Center Green Bay
Green Bay, Wisconsin, United States
Withdrawn
Dean Hematology and Oncology Clinic
Madison, Wisconsin, United States
Withdrawn

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 20 Feb 2020
Primary completion: 15 Jan 2025
Completion: 15 Jan 2025
Last update posted: 18 Dec 2023
Registered enrollment: 480
Registry id: NCT04197687

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.