Clinical trialNCT05987241RecruitingPhase 2/PHASE3Interventional

Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study

SponsorNational Cancer Institute (NCI)Enrollment992Muscle Invasive Bladder Urothelial CarcinomaMuscle Invasive Renal Pelvis Urothelial CarcinomaMuscle Invasive Ureter Urothelial CarcinomaMuscle Invasive Urethral Urothelial CarcinomaStage II Bladder Urothelial Carcinoma AJCC v6 and v7Stage III Bladder Urothelial Carcinoma AJCC v6 and v7+1 more conditions

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Matthew D Galsky
Alliance for Clinical Trials in Oncology
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

499 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada

Arthur J E Child Comprehensive Cancer Centre
Calgary, Alberta, Canada
Nimira S. Alimohamed
Recruiting
Cross Cancer Institute
Edmonton, Alberta, Canada
Scott A. North
Recruiting
Bcca-Vancouver Cancer Centre
Vancouver, British Columbia, Canada
Bernie (Bernhard) J. Eigl
Recruiting
Waterloo Regional Health Network
Kitchener, Ontario, Canada
Anupam Batra
Recruiting
London Regional Cancer Program
London, Ontario, Canada
Melissa Huynh
Recruiting
Ottawa Hospital and Cancer Center-General Campus
Ottawa, Ontario, Canada
Ana-Alicia Beltran-Bless
Recruiting
Odette Cancer Centre- Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
Susanna Y. Cheng
Recruiting
University Health Network-Princess Margaret Hospital
Toronto, Ontario, Canada
Srikala S. Sridhar
Recruiting

United States

Cancer Center at Saint Joseph'S
Phoenix, Arizona, United States
Shahzad Siddique
Recruiting
Mayo Clinic Hospital in Arizona
Phoenix, Arizona, United States
Arnab Basu
Recruiting
Banner University Medical Center - Tucson
Tucson, Arizona, United States
Edward P. Gelmann
Recruiting
University of Arizona Cancer Center-North Campus
Tucson, Arizona, United States
Edward P. Gelmann
Recruiting
University of Arizona Cancer Center-Orange Grove Campus
Tucson, Arizona, United States
Suspended
Highlands Oncology Group - Fayetteville
Fayetteville, Arkansas, United States
Joseph T. Beck
Recruiting
Highlands Oncology Group - Rogers
Rogers, Arkansas, United States
Joseph T. Beck
Recruiting
Highlands Oncology Group
Springdale, Arkansas, United States
Joseph T. Beck
Recruiting
Kaiser Permanente-Anaheim
Anaheim, California, United States
Helen H. Moon
Recruiting
Kaiser Permanente-Baldwin Park
Baldwin Park, California, United States
Helen H. Moon
Recruiting
Kaiser Permanente-Bellflower
Bellflower, California, United States
Helen H. Moon
Recruiting
Kaiser Permanente Dublin
Dublin, California, United States
Andrea L. Harzstark
Recruiting
Kaiser Permanente-Fontana
Fontana, California, United States
Helen H. Moon
Recruiting
Kaiser Permanente-Fremont
Fremont, California, United States
Andrea L. Harzstark
Recruiting
Kaiser Permanente Fresno Orchard Plaza
Fresno, California, United States
Andrea L. Harzstark
Recruiting
Kaiser Permanente-Fresno
Fresno, California, United States
Andrea L. Harzstark
Recruiting
Kaiser Permanente South Bay
Harbor City, California, United States
Helen H. Moon
Recruiting
Kaiser Permanente-Irvine
Irvine, California, United States
Helen H. Moon
Recruiting
Uc San Diego Moores Cancer Center
La Jolla, California, United States
Tyler Stewart
Recruiting
Kaiser Permanente Los Angeles Medical Center
Los Angeles, California, United States
Helen H. Moon
Recruiting
Kaiser Permanente West Los Angeles
Los Angeles, California, United States
Helen H. Moon
Recruiting
Keck Medicine of Usc Koreatown
Los Angeles, California, United States
Active, not recruiting
Los Angeles General Medical Center
Los Angeles, California, United States
Active, not recruiting
Ucla / Jonsson Comprehensive Cancer Center
Los Angeles, California, United States
Alexandra Drakaki
Recruiting
Usc / Norris Comprehensive Cancer Center
Los Angeles, California, United States
Active, not recruiting
Kaiser Permanente- Modesto Mob Ii
Modesto, California, United States
Andrea L. Harzstark
Recruiting
Kaiser Permanente-Modesto
Modesto, California, United States
Andrea L. Harzstark
Recruiting
Usc Norris Oncology/hematology-Newport Beach
Newport Beach, California, United States
Active, not recruiting
Kaiser Permanente-Oakland
Oakland, California, United States
Andrea L. Harzstark
Recruiting
Kaiser Permanente-Ontario
Ontario, California, United States
Helen H. Moon
Recruiting
Stanford Cancer Institute Palo Alto
Palo Alto, California, United States
Ali R. Khaki
Recruiting
Kaiser Permanente - Panorama City
Panorama City, California, United States
Helen H. Moon
Recruiting

459 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Nivolumab →Relatlimab

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 2 Feb 2024
Primary completion: 2 Sept 2030
Completion: 2 Sept 2030
Last update posted: 7 Jul 2026
Registered enrollment: 992
Registry id: NCT05987241

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.