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Clinical trialNCT04281498CompletedPhase 2Interventional

Combined Ruxolitinib and Enasidenib in Patients With Accelerated/Blast-phase Myeloproliferative Neoplasm or Chronic-phase Myelofibrosis With an IDH2 Mutation

SponsorJohn MascarenhasEnrollment6Accelerated/Blast-phase Myeloproliferative NeoplasmChronic-phase MyelofibrosisIDH2 Mutation
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

11 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • Princess Margaret Cancer Centre

    Toronto, Canada

United States
  • Mayo Clinic - Arizona

    Scottsdale, Arizona, United States

  • Cedars-Sinai Medical Center

    Los Angeles, California, United States

  • Moffitt Cancer Center

    Tampa, Florida, United States

  • University of Kansas Cancer Center

    Westwood, Kansas, United States

  • University of Michigan Rogel Cancer Center

    Ann Arbor, Michigan, United States

  • Icahn School of Medicine at Mount Sinai

    New York, New York, United States

  • Memorial Sloan-Kettering Cancer Center

    New York, New York, United States

  • Wake Forest Baptist Health

    Winston-Salem, North Carolina, United States

  • Taussig Cancer Center Institute

    Cleveland, Ohio, United States

  • Mays Cancer Center at Ut Health San Antonio

    San Antonio, Texas, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
14 Jan 2021
Primary completion
30 May 2023
Completion
30 May 2023
Last update posted
4 Feb 2025
Registered enrollment
6
Registry id
NCT04281498

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.