findmyKOL
Clinical trialNCT07447817Not, yet, recruitingPhase 2Interventional

Selinexor and Pacritinib in JAK Inhibitor-naïve MF Patients With Cytopenias

SponsorJohn MascarenhasEnrollment26MyelofibrosisPost-essential Thrombocythemia MyelofibrosisPost-polycythemia Vera Myelofibrosis
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a phase II, multicenter, open-label trial evaluating the safety and efficacy of pacritinib and selinexor in JAK inhibitor naïve patients with anemia and thrombocytopenia.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

3 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • the University of Kansas Cancer Center-Westwood

    Westwood, Kansas, United States

    Abdulraheem Yacoub
  • Icahn School of Medicine at Mount Sinai

    New York, New York, United States

    John Mascarenhas
  • Wake Forest Baptist Health Comprehensive Cancer Center

    Winston-Salem, North Carolina, United States

    Ruben Mesa

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Pacritinib →Selinexor →
Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
4 May 2026
Primary completion
24 May 2030
Completion
24 May 2030
Last update posted
18 Mar 2026
Registered enrollment
26
Registry id
NCT07447817
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.