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Clinical trialNCT04321759UnknownInterventional

Comparative Effectiveness of CET vs. SST in SMI (Serious Mental Illness)

SponsorBeth Israel Deaconess Medical CenterEnrollment378Schizophrenia and Related Disorders
View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

To compare two evidence-based treatments, Cognitive Enhancement Therapy (CET) and Social Skills Training (SST) that have been shown in meta-analyses and in our own research to be effective to improve community functioning. The investigators will test the impact of CET and SST on community functioning, with special attention to their relative effectiveness for patients differing in baseline cognitive skills and age. The research uses a cluster design in which different mental health service centers are randomized to one of the two treatments.
clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Hartford Hospital - Institute of Living

    Hartford, Connecticut, United States

    Recruiting
  • Maine Medical Center

    Portland, Maine, United States

    Recruiting
  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, United States

    Active, not recruiting
  • Massachusetts Mental Health Center

    Boston, Massachusetts, United States

    Recruiting
  • Umass Medical School

    Worcester, Massachusetts, United States

    Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
1 Jun 2021
Primary completion
31 Jan 2026
Completion
31 Jan 2026
Last update posted
14 Nov 2023
Registered enrollment
378
Registry id
NCT04321759
clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.