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Clinical trialNCT04533750Active, not recruitingPhase 1Interventional

Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take Cisplatin

SponsorNational Cancer Institute (NCI)Enrollment21Advanced Head and Neck Squamous Cell CarcinomaAdvanced Hypopharyngeal Squamous Cell CarcinomaAdvanced Laryngeal Squamous Cell CarcinomaAdvanced Oral Cavity Squamous Cell CarcinomaAdvanced Oropharyngeal Squamous Cell CarcinomaClinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+12 more conditions
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

27 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States
  • Banner Md Anderson Cancer Center

    Gilbert, Arizona, United States

  • Mayo Clinic Hospital in Arizona

    Phoenix, Arizona, United States

  • Banner University Medical Center - Tucson

    Tucson, Arizona, United States

  • University of Arizona Cancer Center-North Campus

    Tucson, Arizona, United States

  • Uc San Diego Moores Cancer Center

    La Jolla, California, United States

  • Stanford Cancer Institute Palo Alto

    Palo Alto, California, United States

  • University of Miami Miller School of Medicine-Sylvester Cancer Center

    Miami, Florida, United States

  • Moffitt Cancer Center

    Tampa, Florida, United States

  • Emory University Hospital Midtown

    Atlanta, Georgia, United States

  • Emory University Hospital/winship Cancer Institute

    Atlanta, Georgia, United States

  • Carle at the Riverfront

    Danville, Illinois, United States

  • Carle Physician Group-Effingham

    Effingham, Illinois, United States

  • Carle Physician Group-Mattoon/charleston

    Mattoon, Illinois, United States

  • Carle Cancer Center

    Urbana, Illinois, United States

  • the James Graham Brown Cancer Center at University of Louisville

    Louisville, Kentucky, United States

  • Nyu Langone Hospital - Long Island

    Mineola, New York, United States

  • Laura and Isaac Perlmutter Cancer Center at Nyu Langone

    New York, New York, United States

  • Highland Hospital

    Rochester, New York, United States

  • University of Rochester

    Rochester, New York, United States

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, United States

  • Providence Portland Medical Center

    Portland, Oregon, United States

  • Medical University of South Carolina

    Charleston, South Carolina, United States

  • Sanford Cancer Center Oncology Clinic

    Sioux Falls, South Dakota, United States

  • Sanford Usd Medical Center - Sioux Falls

    Sioux Falls, South Dakota, United States

  • Ut Md Anderson Cancer Center

    Houston, Texas, United States

  • Inova Schar Cancer Institute

    Fairfax, Virginia, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
20 Dec 2021
Primary completion
7 Dec 2025
Completion
15 Dec 2026
Last update posted
17 Jun 2026
Registered enrollment
21
Registry id
NCT04533750

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.