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Clinical trialNCT04588246TerminatedPhase 3Interventional

Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery

SponsorNRG OncologyEnrollment19Anatomic Stage IV Breast Cancer AJCC v8Metastatic Lung Non-Small Cell CarcinomaMetastatic Lung Small Cell CarcinomaMetastatic Malignant Breast NeoplasmMetastatic Malignant Digestive System NeoplasmMetastatic Malignant Neoplasm in the Brain+6 more conditions
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

81 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Canada
  • Chum - Centre Hospitalier de L'Universite de Montreal

    Montreal, Quebec, Canada

Hong Kong
  • Pamela Youde Nethersole Eastern Hospital

    Chai Wan, Hong Kong

United States
  • Banner University Medical Center - Tucson

    Tucson, Arizona, United States

  • University of Arizona Cancer Center-North Campus

    Tucson, Arizona, United States

  • City of Hope Corona

    Corona, California, United States

  • City of Hope Comprehensive Cancer Center

    Duarte, California, United States

  • City of Hope at Irvine Lennar

    Irvine, California, United States

  • City of Hope Antelope Valley

    Lancaster, California, United States

  • Sutter Cancer Centers Radiation Oncology Services-Roseville

    Roseville, California, United States

  • Sutter Roseville Medical Center

    Roseville, California, United States

  • Sutter Medical Center Sacramento

    Sacramento, California, United States

  • California Pacific Medical Center-Pacific Campus

    San Francisco, California, United States

  • City of Hope South Pasadena

    South Pasadena, California, United States

  • City of Hope South Bay

    Torrance, California, United States

  • City of Hope Upland

    Upland, California, United States

  • Christiana Care Health System-Christiana Hospital

    Newark, Delaware, United States

  • Delaware Clinical and Laboratory Physicians Pa

    Newark, Delaware, United States

  • Helen F Graham Cancer Center

    Newark, Delaware, United States

  • Medical Oncology Hematology Consultants Pa

    Newark, Delaware, United States

  • Um Sylvester Comprehensive Cancer Center at Coral Gables

    Coral Gables, Florida, United States

  • Um Sylvester Comprehensive Cancer Center at Deerfield Beach

    Deerfield Beach, Florida, United States

  • Mayo Clinic in Florida

    Jacksonville, Florida, United States

  • University of Miami Miller School of Medicine-Sylvester Cancer Center

    Miami, Florida, United States

  • Memorial Hospital West

    Pembroke Pines, Florida, United States

  • Northwestern University

    Chicago, Illinois, United States

  • Rush University Medical Center

    Chicago, Illinois, United States

  • University of Chicago Comprehensive Cancer Center

    Chicago, Illinois, United States

  • Carle at the Riverfront

    Danville, Illinois, United States

  • Northwestern Medicine Cancer Center Kishwaukee

    DeKalb, Illinois, United States

  • Carle Physician Group-Effingham

    Effingham, Illinois, United States

  • Northwestern Medicine Cancer Center Delnor

    Geneva, Illinois, United States

  • Carle Physician Group-Mattoon/charleston

    Mattoon, Illinois, United States

  • Carle Cancer Center

    Urbana, Illinois, United States

  • the Carle Foundation Hospital

    Urbana, Illinois, United States

  • Northwestern Medicine Cancer Center Warrenville

    Warrenville, Illinois, United States

  • Medstar Franklin Square Medical Center/weinberg Cancer Institute

    Baltimore, Maryland, United States

  • University of Maryland/greenebaum Cancer Center

    Baltimore, Maryland, United States

  • Um Upper Chesapeake Medical Center

    Bel Air, Maryland, United States

  • Central Maryland Radiation Oncology in Howard County

    Columbia, Maryland, United States

  • Um Baltimore Washington Medical Center/tate Cancer Center

    Glen Burnie, Maryland, United States

41 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
5 Aug 2021
Primary completion
6 Aug 2024
Completion
6 Aug 2024
Last update posted
20 May 2026
Registered enrollment
19
Registry id
NCT04588246

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.