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Clinical trialNCT04739761Active, not recruitingPhase 3Interventional

A Study of T-DXd in Participants With or Without Brain Metastasis Who Have Previously Treated Advanced or Metastatic HER2 Positive Breast Cancer

SponsorAstraZenecaEnrollment506Breast Cancer
View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

  • Nadia Harbeck, MD, PhD

    Head, Breast Center, Ludwig-Maximilians-University of Munich Department of Obstetrics and Gynecology Marchioninistr. 15, 81377 Munich, Germany

    Principal Investigator
  • Nancy U. Lin, MD

    Associate Chief, Division of Breast Oncology, Susan F. Smith Center for Women's Cancers Director, Metastatic Breast Cancer Program, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215

    Principal Investigator

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

81 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Australia
  • Research Site

    Adelaide, Australia

  • Research Site

    Auchenflower, Australia

  • Research Site

    Clayton, Australia

  • Research Site

    Heidelberg, Australia

  • Research Site

    St Leonards, Australia

  • Research Site

    Subiaco, Australia

Belgium
  • Research Site

    Anderlecht, Belgium

  • Research Site

    Bruges, Belgium

  • Research Site

    Leuven, Belgium

  • Research Site

    Liège, Belgium

Canada
  • Research Site

    Vancouver, British Columbia, Canada

  • Research Site

    Toronto, Ontario, Canada

Denmark
  • Research Site

    Copenhagen, Denmark

  • Research Site

    Herlev, Denmark

  • Research Site

    Odense C, Denmark

Finland
  • Research Site

    Helsinki, Finland

  • Research Site

    Tampere, Finland

  • Research Site

    Turku, Finland

Germany
  • Research Site

    Berlin, Germany

  • Research Site

    Dresden, Germany

  • Research Site

    Erlangen, Germany

  • Research Site

    Essen, Germany

  • Research Site

    Frankfurt, Germany

  • Research Site

    Hamburg, Germany

  • Research Site

    Hanover, Germany

  • Research Site

    Kiel, Germany

  • Research Site

    Mannheim, Germany

  • Research Site

    München, Germany

  • Research Site

    München, Germany

  • Research Site

    Münster, Germany

  • Research Site

    Tübingen, Germany

Ireland
  • Research Site

    Cork, Ireland

  • Research Site

    Dublin, Ireland

  • Research Site

    Dublin, Ireland

Italy
  • Research Site

    Ancona, Italy

  • Research Site

    Bergamo, Italy

  • Research Site

    Catania, Italy

  • Research Site

    Milan, Italy

  • Research Site

    Naples, Italy

  • Research Site

    Padova, Italy

41 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start
22 Jun 2021
Primary completion
8 Feb 2024
Completion
26 May 2027
Last update posted
12 May 2026
Registered enrollment
506
Registry id
NCT04739761

Cross-registrations

EU-CTR / CTIS (EudraCT)2020-005048-46EU-CTR / CTIS (EudraCT)2024-510588-53-00

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.