Clinical trialNCT05386108RecruitingPhase 1/PHASE2Interventional

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

SponsorStemline Therapeutics, Inc.Enrollment73Brain DiseasesBrain NeoplasmsBreast DiseasesBreast NeoplasmsCentral Nervous System DiseasesCentral Nervous System Neoplasms+2 more conditions

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

86 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Belgium

Antwerp University Hospital
Edegem, Belgium
Konstantinos Papadimitriou
Recruiting
Universitaire Ziekenhuizen Leuven - Campus Gasthuisberg
Leuven, Belgium
Patrick Neven
Recruiting
Universite Catholique de Louvain (ucl) - Cliniques Universitaires Saint-Luc
Woluwe-Saint-Lambert, Belgium
Francois Duhoux
Recruiting

France

Institut de Cancerologie de L'Ouest Site Paul Papin
Angers, France
Paule Augereau
Recruiting
Hôpital Morvan - Chru de Brest - Cancérologie Et D'Hématologie
Brest, France
Laura Deiana
Recruiting
Centre Francois Baclesse - Oncologie Medicale - Cancerolo
Caen, France
George Emile
Recruiting
Centre Jean Perrin
Clermont-Ferrand, France
Marie-Ange Mouret-Reynier
Recruiting
Centre Léon Bérard - Département Oncologie Médicale
Lyon, France
Louis Larrouquere
Recruiting
Centre de Cancerologie Du Grand Montpellier
Montpellier, France
Cristian Villanueva
Recruiting
Hôpital de la Pitiê Salpêtriêre
Paris, France
Tichoue Herve Foka
Recruiting
Centre Hospitalier Universitaire de Poitiers
Poitiers, France
Nicolas Isambert
Recruiting
Institut Claudius Regaud
Toulouse, France
Florence Dalenc
Recruiting

Germany

Klinikum Bayreuth Gmbh
Bayreuth, Germany
Christoph Mundhenke
Recruiting
Uniklinik Koeln - Klinik Und Poliklinik Fuer Frauenheilkunde
Cologne, Germany
Completed
Universitatsklinikum Carl Gustav Carus
Dresden, Germany
Pauline Wimberger
Recruiting
Universitaetsklinikum Duesseldorf
Düsseldorf, Germany
Tanja Fehm
Recruiting
Universitätsklinikum Erlangen
Erlangen, Germany
Peter Fasching
Recruiting
Medizinische Hochschule Hannover
Hanover, Germany
Tjoung-Won Park-Simon
Recruiting
Universitätsklinikum Leipzig
Leipzig, Germany
Dirk Forstmeyer
Recruiting
Klinikum Worms Ggmbh
Worms, Germany
Eva Werner
Recruiting
Helios Klinikum Wuppertal
Wuppertal, Germany
Vesna Bjelic-Radisic
Recruiting

Greece

National and Capodistrian University of Athens - University General Hospital Attikon
Athens, Greece
Anna Koumarianou
Recruiting
Metropolitan Hospital [oncology]
Piraeus, Greece
Eleni Linardou
Recruiting
Euromedica General Clinic of Thessaloniki
Thessaloniki, Greece
Completed
Interbalkan European Medical Center
Thessaloniki, Greece
Sofia Baka
Recruiting

Italy

Aou Ospedali Riuniti Umberto I-G.M.Lancisi -G.Salesi
Ancona, Italy
Rossana Berardi
Recruiting
Istituto Di Candiolo, Irccs
Candiolo, Italy
Vanesa Gregorc
Recruiting
Istituto Romagnolo Per Lo Studio Dei Tumori Dino Amadori - Irst Irccs
Meldola, Italy
Michela Palleschi
Recruiting
A. O. Ospedali Riuniti Parpardo, Piemonte, Messina
Messina, Italy
Ricciardi Giuseppina
Recruiting
Ieo - Istituto Europeo Di Oncologia, Irccs
Milan, Italy
Giuseppe Curigliano
Recruiting
Azienda Ospedaliero-Universitaria Di Modena, Policlinico Di Modena
Modena, Italy
Annalisa Fontana
Recruiting
Ospedale San Gerardo, Asst Di Monza, Irccs
Monza, Italy
Marina Cazzaniga
Recruiting
Azienda Ospedaliera Universitaria Federico Ii
Naples, Italy
Mario Giuliano
Recruiting
Istituto Nazionale Dei Tumori - Fondazione Pascale, Irccs
Naples, Italy
Michelino De Laurentiis
Recruiting
Istituto Oncologico Veneto Iov - Irccs
Padova, Italy
Valentina Guarneri
Recruiting
Irccs Policlinico San Matteo, Università Degli Studi Di Pavia, Pavia Fondazione Irccs Policlinico San Matteo
Pavia, Italy
Angioletta Lasagna
Recruiting
Fondazione Policlinico Universitario Agostino Gemelli Irccs
Roma, Italy
Alessandra Fabi
Recruiting
Azienda Ospedaliera Santa Maria Di Terni
Terni, Italy
Jennifer Foglietta
Recruiting
Aou Città Della Salute E Della Scienza Di Torino, Ospedale Molinette
Torino, Italy
Massimiliano Icardi
Recruiting

South Korea

Asan Medical Center
Seoul, South Korea
Sung-Bae Kim
Recruiting

46 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study — it may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 31 Aug 2022
Primary completion: 31 Dec 2026
Completion: 31 Dec 2026
Last update posted: 4 Jun 2026
Registered enrollment: 73
Registry id: NCT05386108

Cross-registrations

EU-CTR / CTIS (EudraCT)2024-512878-98-00

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.