Clinical trialNCT04988555RecruitingPhase 1/PHASE2Interventional

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

SponsorSumitomo Pharma America, Inc.Enrollment606Leukemia, Lymphocytic, AcuteLeukemia, Myeloid, AcuteMultiple MyelomaMyelodysplastic Syndromes

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

No overall officials are registered on this study record. Site-level investigators, where published, appear with their sites below. Why? →

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

104 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

Belgium

Zna Cadix
Antwerp, Belgium
Recruiting
Uz Ghent
Ghent, Belgium
Ine Moors, MD
Recruiting
University Hospitals Leuven
Leuven, Belgium
Johan Maertens, MD
Recruiting
Az Delta
Roeselare, Belgium
Dries Deeren, MD
Recruiting

Canada

Tom Baker Cancer Center
Calgary, Alberta, Canada
Lynn Savoie, MD
Recruiting
University of Alberta
Edmonton, Canada
Joseph Brandwein, MD
Recruiting

France

Centre Hospitalier Universitaire D'Angers
Angers, France
Corentin Orvain, MD
Recruiting
Hopital Avicenne
Bobigny, France
Not, yet, recruiting
Centre Hospitalier Le Mans
Le Mans, France
Recruiting
Hopital Claude Huriez
Lille, France
Not, yet, recruiting
Centre Hospitalier Universitaire de Limoges
Limoges, France
Recruiting
Hospices Civils de Lyon
Lyon, France
Recruiting
Institut Paoli-Calmettes
Marseille, France
Sylvain Garciaz, MD
Recruiting
Chu de Nantes
Nantes, France
Not, yet, recruiting
Chu de Nice - Hôpital L'Archet 1
Nice, France
Thomas Cluzeau, MD
Recruiting
Hopital Saint-Louis
Paris, France
Emmanuel Raffoux, MD
Recruiting
Chu Bordeaux
Talence, France
Not, yet, recruiting
Institut Gustave Roussy
Villejuif, France
Not, yet, recruiting

Italy

Irccs Azienda Ospedaliero-Universitaria Di Bologna, Policlinico Sant'Orsola
Bologna, Italy
Cristina Papayannidis, MD
Recruiting
Ospedale Di Busto Arsizio
Busto Arsizio, Italy
Not, yet, recruiting
Ospedale Policlinico San Martino, Irccs
Genoa, Italy
Recruiting
Irccs Istituto Romagnolo Per Lo Studio Dei Tumori "dino Amadori"
Meldola, Italy
Recruiting
Istituto Oncologico Veneto (iov), Irccs
Padua, Italy
Not, yet, recruiting
Università Degli Studi Di Perugia
Perugia, Italy
Recruiting
Azienda Usl Della Romagna, Ospedale Santa Maria Delle Croci Di Ravenna
Ravenna, Italy
Not, yet, recruiting
Pu A. Gemelli, Università Cattolica del Sacro Cuore
Rome, Italy
Recruiting
Universita' Degli Studi Di Torino
Turin, Italy
Recruiting

Japan

National Cancer Center Hospital East
Kashiwa-shi, Chiba, Japan
Junichiro Yuda, MD
Recruiting
University of Fukui Hospital
Yoshida-gun, Fukui, Japan
Naoko Hosono, MD
Recruiting
Fukushima Medical University Hospital
Fukushima, Fukushima, Japan
Takayuki Ikezoe, MD
Recruiting
Tokai University Hospital
Isehara-shi, Kanagawa, Japan
Yoshiaki Ogawa, MD
Recruiting
Nagasaki University Hospital
Nagasaki, Nagasaki, Japan
Yasushi Miyazaki, MD
Recruiting
Nippon Medical School Hospital
Bunkyo-ku, Tokyo, Japan
Hiroki Yamaguchi, MD
Recruiting
Tokyo Metropolitan Komagome Hospital
Bunkyō City, Japan
Not, yet, recruiting
Kyushu University Hospital
Fukuoka, Japan
Takahiro Shima, MD
Recruiting
Hokkaido University Hospital
Hokkaido, Japan
Takanori Teshima, MD
Not, yet, recruiting
Tohoku University Hospital
Miyagi, Japan
Hisayuki Yokoyama, MD
Recruiting
Okayama University Hospital
Okayama, Japan
Noboru Asada, MD
Recruiting
Osaka University Hospital
Osaka, Japan
Kentaro Fukushima, MD
Recruiting

Singapore

National University Cancer Institute
Singapore, Singapore
Melissa Ooi, MD
Recruiting

64 more sites on the registry record.ClinicalTrials.gov ↗

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Azacitidine →Dsp-5336Gilteritinib →Intensive chemotherapy with 7 + 3Venetoclax →Azoles

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 28 Feb 2022
Primary completion: 30 Jun 2027
Completion: 31 Dec 2027
Last update posted: 24 Mar 2026
Registered enrollment: 606
Registry id: NCT04988555

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.