Clinical trialNCT05025787CompletedPhase 2Interventional

A Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Knee Osteoarthritis Pain.

SponsorMaurizio Fava, MDEnrollment55Knee Osteoarthritis

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The primary objective of this study is to evaluate the safety and efficacy of CNTX-6970 for the treatment of pain related to OA of the knee compared to placebo. CNTX-6970 is being developed as a new treatment for chronic pain, including painful osteoarthritis of the knee.

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Maurizio Fava, MD
Massachusetts General Hosptial
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

16 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of California San Diego
La Jolla, California, United States
University of California- Davis
Sacramento, California, United States
University of Florida
Gainesville, Florida, United States
M&m Clinical Trials
Miami, Florida, United States
Massachusetts General Hospital
Boston, Massachusetts, United States
Healthcare Research Network
Hazelwood, Missouri, United States
Icahn School of Medicine at Mount Sinai
New York, New York, United States
New York University Langone Health
New York, New York, United States
University of Rochester
Rochester, New York, United States
Montefiore Medical Center
The Bronx, New York, United States
Center for Clinical Research
Winston-Salem, North Carolina, United States
University of Pennsylvania
Philadelphia, Pennsylvania, United States
University of Pittsburgh
Pittsburgh, Pennsylvania, United States
Utsouthwestern Medical Center
Dallas, Texas, United States
University of Washington
Seattle, Washington, United States
University of Wisconsin- Madison
Madison, Wisconsin, United States

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

CNTX-6970Placebo

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 25 Oct 2021
Primary completion: 11 Jun 2024
Completion: 11 Jun 2024
Last update posted: 26 Nov 2025
Registered enrollment: 55
Registry id: NCT05025787

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.