Clinical trialNCT05197881RecruitingInterventional

Daily Adaptive Radiation Therapy an Individualized Approach for Carcinoma of the Cervix

SponsorVarian, a Siemens Healthineers CompanyEnrollment125Cervical Cancer by FIGO Stage 2018

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

This is a single-arm, prospective, multi-center clinical trial designed to demonstrate that adaptive radiotherapy for locally advanced cervical cancer will translate into a decreased rate of acute gastrointestinal toxicity compared with the historically reported rate for non-adaptive intensity modulated radiation therapy (IMRT). The timepoint for this assessment will be at week 5 of external beam radiotherapy (EBRT) and will use the Patient-Reported Outcomes version of the Common Terminology Criteria for Adverse Events (PRO-CTCAE).

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Jyoti Mayadev, MD
University of California, San Diego
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗
Xenia Ray, PhD
University of California, San Diego
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

5 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Alabama Birmingham
Burmingham, Alabama, United States
Recruiting
University of Arkansas Medical Sciences
Little Rock, Arkansas, United States
Recruiting
Moores Cancer Center at Uc San Diego Health
La Jolla, California, United States
Recruiting
Fox Chase Cancer Center
Philadelphia, Pennsylvania, United States
Recruiting
University of Texas Southwestern
Dallas, Texas, United States
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 3 May 2022
Primary completion: 30 Sept 2028
Completion: 30 Sept 2030
Last update posted: 23 Sept 2025
Registered enrollment: 125
Registry id: NCT05197881

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.