Clinical trialNCT05198830RecruitingPhase 2Interventional

Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

SponsorNational Cancer Institute (NCI)Enrollment42Lung AdenocarcinomaLung Large Cell CarcinomaLung Non-Squamous Non-Small Cell CarcinomaStage III Lung Cancer AJCC v8

View the registry record on ClinicalTrials.gov

Summary

The registered summary isn't in our current data snapshot. Read it on the ClinicalTrials.gov record ↗. Why? →

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Afshin Dowlati
Case Western Reserve University
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

34 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

Keck Medicine of Usc Buena Park
Buena Park, California, United States
Jason C. Ye
Recruiting
City of Hope Comprehensive Cancer Center
Duarte, California, United States
Jyoti Malhotra →
Recruiting
City of Hope at Irvine Lennar
Irvine, California, United States
Jyoti Malhotra →
Recruiting
City of Hope Antelope Valley
Lancaster, California, United States
Jyoti Malhotra →
Recruiting
Los Angeles General Medical Center
Los Angeles, California, United States
Jason C. Ye
Recruiting
Usc / Norris Comprehensive Cancer Center
Los Angeles, California, United States
Jason C. Ye
Recruiting
Usc Norris Oncology/hematology-Newport Beach
Newport Beach, California, United States
Jason C. Ye
Recruiting
University of California Davis Comprehensive Cancer Center
Sacramento, California, United States
Surbhi Singhal
Recruiting
City of Hope South Pasadena
South Pasadena, California, United States
Jyoti Malhotra →
Recruiting
City of Hope Upland
Upland, California, United States
Jyoti Malhotra →
Recruiting
Um Sylvester Comprehensive Cancer Center at Coral Gables
Coral Gables, Florida, United States
Richa Dawar
Recruiting
Um Sylvester Comprehensive Cancer Center at Deerfield Beach
Deerfield Beach, Florida, United States
Richa Dawar
Recruiting
Uf Health Cancer Institute - Gainesville
Gainesville, Florida, United States
Tithi Biswas
Recruiting
Um Sylvester Comprehensive Cancer Center at Kendall
Miami, Florida, United States
Richa Dawar
Recruiting
University of Miami Miller School of Medicine-Sylvester Cancer Center
Miami, Florida, United States
Richa Dawar
Recruiting
Um Sylvester Comprehensive Cancer Center at Plantation
Plantation, Florida, United States
Richa Dawar
Recruiting
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, United States
Everett E. Vokes →
Recruiting
Uc Comprehensive Cancer Center at Silver Cross
New Lenox, Illinois, United States
Everett E. Vokes →
Recruiting
University of Chicago Medicine-Orland Park
Orland Park, Illinois, United States
Everett E. Vokes →
Recruiting
Uchicago Medicine Northwest Indiana
Crown Point, Indiana, United States
Everett E. Vokes →
Recruiting
Jersey City Medical Center
Jersey City, New Jersey, United States
Salma K. Jabbour
Recruiting
Saint Barnabas Medical Center
Livingston, New Jersey, United States
Salma K. Jabbour
Recruiting
Monmouth Medical Center
Long Branch, New Jersey, United States
Salma K. Jabbour
Recruiting
Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, United States
Salma K. Jabbour
Recruiting
Newark Beth Israel Medical Center
Newark, New Jersey, United States
Salma K. Jabbour
Recruiting
Robert Wood Johnson University Hospital Somerset
Somerville, New Jersey, United States
Salma K. Jabbour
Recruiting
Community Medical Center
Toms River, New Jersey, United States
Salma K. Jabbour
Recruiting
Montefiore Medical Center - Moses Campus
The Bronx, New York, United States
Active, not recruiting
Montefiore Medical Center-Einstein Campus
The Bronx, New York, United States
Active, not recruiting
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States
Thomas W. Lycan
Recruiting
Case Western Reserve University
Cleveland, Ohio, United States
Afshin Dowlati →
Recruiting
Metrohealth Medical Center
Cleveland, Ohio, United States
Peter Xie
Recruiting
University of Pittsburgh Cancer Institute (upci)
Pittsburgh, Pennsylvania, United States
Liza C. Villaruz
Recruiting
University of Texas Medical Branch
Galveston, Texas, United States
Suspended

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

The drug and biological interventions registered on this study, normalized to their RxNorm ingredient where possible.

Carboplatin →Cisplatin →Durvalumab →O-MethylhydroxylaminePemetrexed →

Linked drugs open the directory filtered to KOLs working with them.clinicaltrials.gov ↗

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 15 Dec 2022
Primary completion: 30 Jun 2027
Completion: 30 Jun 2027
Last update posted: 11 Jun 2026
Registered enrollment: 42
Registry id: NCT05198830

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 12 Jul 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.