Clinical trialNCT05265520RecruitingInterventional

His-Bundle Corrective Pacing in Heart Failure

SponsorUniversity of RochesterEnrollment120Cardiac Resynchronization TherapyHeart FailureHis-bundle PacingRight Bundle-Branch Block

View the registry record on ClinicalTrials.gov

Summary

The lay summary the sponsor registered on ClinicalTrials.gov.

The investigators aim to prospectively evaluate the efficacy and mechanism of benefit of His-bundle pacing enhanced cardiac resynchronization therapy (His-CRT) vs. cardiac resynchronization therapy (BIV-CRT) in patients with heart failure and right bundle branch block (RBBB).

clinicaltrials.gov ↗

Investigators

The overall officials registered on this study. Names that resolve to a findmyKOL profile link to it; the rest are shown as registered.

Roderick Tung, MD
University of Arizona
Principal InvestigatorKOL profile →
clinicaltrials.gov ↗
Valentina Kutyifa, MD, PhD
University of Rochester
Principal Investigator
clinicaltrials.gov ↗

A profile link is shown only when the registered name resolves to a person record with a confident, namesake-checked match; ambiguous names stay unlinked.

Sites

14 registered facilities, with the per-site recruitment status where the registry publishes one. ClinicalTrials.gov does not publish per-site enrollment counts.

United States

University of Arizona
Phoenix, Arizona, United States
Roderick Tung
Recruiting
Cedars-Sinai Medical Center
Los Angeles, California, United States
Eric Braunstein
Recruiting
University of South Florida
Tampa, Florida, United States
Bengt Herweg
Recruiting
Northwestern Memorial Hospital
Chicago, Illinois, United States
Nishant Verma
Recruiting
Rush University Medical Center
Chicago, Illinois, United States
Timothy Larsen
Recruiting
University of Chicago
Chicago, Illinois, United States
Gaurav Upadhyay →
Recruiting
Valley Health System
Ridgewood, New Jersey, United States
Suneet Mittal →
Recruiting
Mount Sinai Hospital
New York, New York, United States
Jacob Koruth
Recruiting
Weill Cornell Medical College
New York, New York, United States
Jim Cheung
Recruiting
Mission Health
Asheville, North Carolina, United States
Michael Manogue
Recruiting
University of Pennsylvania
Philadelphia, Pennsylvania, United States
Robert Schaller
Recruiting
Geisinger Wyoming Valley
Wilkes-Barre, Pennsylvania, United States
Pugazhendhi Vijayaraman →
Recruiting
University of Vermont
Burlington, Vermont, United States
Recruiting
Virginia Commonwealth University
Richmond, Virginia, United States
Kenneth Ellenbogen
Recruiting

Site investigator names are published by ClinicalTrials.gov only while a study recruits, so completed studies list sites without them.

Drugs studied

No drug or biological interventions are in our data for this study. It may test a procedure, device or behavioral intervention, or the intervention list isn't in our current snapshot. See the registry record ↗. Why? →

Registration & key dates

Registry attributes as recorded on the ClinicalTrials.gov study record.

Start: 2 Dec 2022
Primary completion: 1 Jul 2027
Completion: 1 Jul 2028
Last update posted: 9 Feb 2026
Registered enrollment: 120
Registry id: NCT05265520

clinicaltrials.gov ↗

Source: ClinicalTrials.gov, via the CTTI AACT database, data as of 24 Aug 2026. Registry facts are shown as registered by the study sponsor; findmyKOL does not interpret them.